UniProt Q12959
Q12959
Q12959 (UniProt Q12959): 21 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q12959
- Experimental structures
- 21
- Predicted models
- 1
- Ligands
- 1
Structures
22 records of Q12959 in the MolNFT archive: 21 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1PDR | Crystal structure of the third PDZ domain from the human homolog of discs large protein | x-ray diffraction | A | — | — |
| 1PDR | Crystal structure of the third PDZ domain from the human homolog of discs large protein | x-ray diffraction | A | — | — |
| 2M3M | Solution structure of a complex consisting of hDlg/SAP-97 residues 318-406 and HPV51 oncoprotein E6… | solution nmr | A | — | — |
| 2M3M | Solution structure of a complex consisting of HDLG/SAP-97 residues 318-406 and HPV51 oncoprotein E6… | solution nmr | A | — | — |
| 2OQS | Structure of the hDLG/SAP97 PDZ2 in complex with HPV-18 papillomavirus E6 peptide | solution nmr | A | — | — |
| 2OQS | Structure of the HDLG/SAP97 PDZ2 in complex with HPV-18 papillomavirus E6 peptide | solution nmr | A | — | — |
| 2X7Z | Crystal Structure of the SAP97 PDZ2 I342W C378A mutant protein domain | x-ray diffraction | A | — | — |
| 2X7Z | Crystal structure of the SAP97 PDZ2 I342W C378A mutant protein domain | x-ray diffraction | A | — | — |
| 3LRA | Structural Basis for Assembling a Human Tripartite Complex Dlg1-MPP7-Mals3 | x-ray diffraction | A | — | — |
| 3LRA | Structural basis for assembling a human tripartite complex DLG1-MPP7- MALS3 | x-ray diffraction | A | — | — |
| 3RL7 | Crystal structure of hDLG1-PDZ1 complexed with APC | x-ray diffraction | B, A, C, D, E, F | — | — |
| 3RL7 | Crystal structure of HDLG1-PDZ1 complexed with apc | x-ray diffraction | B, A, C, D, E, F | — | — |
| 3RL8 | Crystal structure of hDLG1-PDZ2 complexed with APC | x-ray diffraction | A, B, C, D, E | — | — |
| 3RL8 | Crystal structure of HDLG1-PDZ2 complexed with apc | x-ray diffraction | A, B, C, D, E | — | — |
| 3W9Y | Crystal structure of the human DLG1 guanylate kinase domain | x-ray diffraction | — | — | |
| 4AMH | Influence of circular permutation on the folding pathway of a PDZ domain | x-ray diffraction | A, B | — | — |
| 4AMH | Influence of circular permutation on the folding pathway of a PDZ domain | x-ray diffraction | A, B | — | — |
| 4G69 | Structure of the Human Discs Large 1 PDZ2 - Adenomatous Polyposis Coli Cytoskeletal Polarity Complex | x-ray diffraction | A | — | — |
| 4G69 | Structure of the human discs large 1 PDZ2 - adenomatous polyposis COLI cytoskeletal polarity complex | x-ray diffraction | A | — | — |
| 7PC3 | The second PDZ domain of DLG1 complexed with the PDZ-binding motif of HTLV1-TAX1 | x-ray diffraction | A | CA | — |
| 8CN3 | hDLG1-PDZ2 in complex with a TAX1 peptide from HTLV-1 | x-ray diffraction | A, B | — | — |
| Q12959 | AlphaFold monomer V2.0 prediction for disks large homolog 1 (Q12959) | predicted | A | — | — |
Ligands
- CA · Calcium ion · in 1 record
Experiment against prediction
- 8CN3 chain B against the predicted model Q12959: TM-score 0.99, RMSD 0.40 Å
- 3RL8 chain E against the predicted model Q12959: TM-score 0.99, RMSD 0.43 Å
- 3RL8 chain E against the predicted model Q12959: TM-score 0.99, RMSD 0.43 Å
- 8CN3 chain A against the predicted model Q12959: TM-score 0.99, RMSD 0.42 Å
- 3RL7 chain E against the predicted model Q12959: TM-score 0.99, RMSD 0.40 Å
- 3RL7 chain E against the predicted model Q12959: TM-score 0.99, RMSD 0.40 Å
- 3RL8 chain B against the predicted model Q12959: TM-score 0.98, RMSD 0.45 Å
- 3RL8 chain B against the predicted model Q12959: TM-score 0.98, RMSD 0.45 Å
- 3RL7 chain C against the predicted model Q12959: TM-score 0.98, RMSD 0.56 Å
- 3RL7 chain C against the predicted model Q12959: TM-score 0.98, RMSD 0.56 Å
Elsewhere
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