UniProt Q12692
Histone H2A.Z (Q12692)
Histone H2A.Z (UniProt Q12692): 6 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q12692
- Protein
- Histone H2A.Z
- Experimental structures
- 6
- Predicted models
- 1
- Ligands
- 1
Structures
7 records of Q12692 in the MolNFT archive: 6 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2JSS | NMR structure of chaperone Chz1 complexed with histone H2A.Z-H2B | solution nmr | A | — | — |
| 2JSS | NMR structure of chaperone CHZ1 complexed with histone H2A.Z-H2B | solution nmr | A | — | — |
| 4M6B | Crystal structure of yeast Swr1-Z domain in complex with H2A.Z-H2B dimer | x-ray diffraction | A, D | — | — |
| 4M6B | Crystal structure of yeast SWR1-Z domain in complex with H2A.Z-H2B dimer | x-ray diffraction | A, D | — | — |
| 6AE8 | Structure insight into histone chaperone CHZ1-mediated H2A.Z recognition and replacement | x-ray diffraction | A, B | BCN | — |
| 8QZ0 | SWR1-hexasome-dimer complex | electron microscopy | L | — | — |
| Q12692 | AlphaFold monomer V2.0 prediction for histone H2A.Z (Q12692) | predicted | A | — | — |
Ligands
- BCN · Bicine · in 1 record
Experiment against prediction
- 8QZ0 chain L against the predicted model Q12692: TM-score 0.89, RMSD 1.44 Å
- 4M6B chain D against the predicted model Q12692: TM-score 0.46, RMSD 1.69 Å
- 4M6B chain D against the predicted model Q12692: TM-score 0.46, RMSD 1.69 Å
- 4M6B chain A against the predicted model Q12692: TM-score 0.46, RMSD 1.61 Å
- 4M6B chain A against the predicted model Q12692: TM-score 0.46, RMSD 1.61 Å
- 6AE8 chain A against the predicted model Q12692: TM-score 0.47, RMSD 1.75 Å
- 6AE8 chain B against the predicted model Q12692: TM-score 0.46, RMSD 1.64 Å
- 2JSS chain A against the predicted model Q12692: TM-score 0.45, RMSD 2.52 Å
- 2JSS chain A against the predicted model Q12692: TM-score 0.45, RMSD 2.52 Å
Elsewhere
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