UniProt Q12488
DNA replication complex GINS protein PSF1 (Q12488)
DNA replication complex GINS protein PSF1 (UniProt Q12488): 18 experimental structures and 1 predicted model on GenesisL1, 9 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q12488
- Protein
- DNA replication complex GINS protein PSF1
- Experimental structures
- 18
- Predicted models
- 1
- Pockets
- 9 · 5 records with a druggable one
Structures
19 records of Q12488 in the MolNFT archive: 18 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 3JC5 | Structure of the eukaryotic replicative CMG helicase and pumpjack motion | electron microscopy | A | — | — |
| 3JC5 | Structure of the eukaryotic replicative cmg helicase and pumpjack motion | electron microscopy | A | — | — |
| 3JC6 | Structure of the eukaryotic replicative CMG helicase and pumpjack motion | electron microscopy | A | — | — |
| 3JC6 | Structure of the eukaryotic replicative cmg helicase and pumpjack motion | electron microscopy | A | — | — |
| 3JC7 | Structure of the eukaryotic replicative CMG helicase and pumpjack motion | electron microscopy | A | — | — |
| 3JC7 | Structure of the eukaryotic replicative cmg helicase and pumpjack motion | electron microscopy | A | — | — |
| 5U8S | Structure of eukaryotic CMG helicase at a replication fork | electron microscopy | A | — | 2 (best 0.83) |
| 5U8S | Structure of eukaryotic cmg helicase at a replication fork | electron microscopy | A | — | — |
| 5U8T | Structure of eukaryotic cmg helicase at a replication fork and implications | electron microscopy | A | — | — |
| 6HV9 | S. cerevisiae cmg-pol epsilon-DNA | electron microscopy | C | — | — |
| 6PTJ | Structure of Ctf4 trimer in complex with one CMG helicase | electron microscopy | A | — | — |
| 6PTJ | Structure of CTF4 trimer in complex with one cmg helicase | electron microscopy | A | — | — |
| 6PTN | Structure of CTF4 trimer in complex with two cmg helicases | electron microscopy | a, A | — | — |
| 6SKL | Cryo-EM structure of the CMG Fork Protection Complex at a replication fork - Conformation 1 | electron microscopy | A | — | 2 (best 0.84) |
| 6U0M | Structure of the S. cerevisiae replicative helicase cmg in complex with a forked DNA | electron microscopy | A | — | — |
| 8B9B | S. cerevisiae replisome + Ctf4, bound by pol alpha. Complex engaged with a fork DNA substrate… | electron microscopy | C | — | — |
| 8P63 | S. cerevisiae consensus-sCMGE on ssDNA after DNA replication initiation | electron microscopy | H | — | 2 (best 0.87) |
| 8W7M | Yeast replisome in state V | electron microscopy | A | — | 2 (best 0.83) |
| Q12488 | AlphaFold monomer V2.0 prediction for DNA replication complex gins protein PSF1 (Q12488) | predicted | A | — | 1 (best 0.50) |
Experiment against prediction
- 8W7M chain A against the predicted model Q12488: TM-score 0.92, RMSD 1.64 Å
- 6SKL chain A against the predicted model Q12488: TM-score 0.91, RMSD 1.82 Å
- 8P63 chain H against the predicted model Q12488: TM-score 0.89, RMSD 2.09 Å
- 6HV9 chain C against the predicted model Q12488: TM-score 0.89, RMSD 2.05 Å
- 8B9B chain C against the predicted model Q12488: TM-score 0.89, RMSD 2.03 Å
- 3JC6 chain A against the predicted model Q12488: TM-score 0.88, RMSD 2.15 Å
- 3JC6 chain A against the predicted model Q12488: TM-score 0.88, RMSD 2.15 Å
- 3JC7 chain A against the predicted model Q12488: TM-score 0.88, RMSD 2.15 Å
- 3JC7 chain A against the predicted model Q12488: TM-score 0.88, RMSD 2.15 Å
- 3JC5 chain A against the predicted model Q12488: TM-score 0.88, RMSD 2.15 Å
Elsewhere
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