UniProt Q12408
PHOSPHATIDYLGLYCEROL/PHOSPHATIDYLINOSITOL transfer protein (Q12408)
PHOSPHATIDYLGLYCEROL/PHOSPHATIDYLINOSITOL transfer protein (UniProt Q12408): 2 experimental structures and 1 predicted model on GenesisL1, 3 ligands bound, 1 pocket. Binding sites, druggability and experiment against prediction…
- UniProt
- Q12408
- Protein
- PHOSPHATIDYLGLYCEROL/PHOSPHATIDYLINOSITOL transfer protein
- Experimental structures
- 2
- Predicted models
- 1
- Ligands
- 3
- Pockets
- 1 · 1 record with a druggable one
Structures
3 records of Q12408 in the MolNFT archive: 2 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 6R4M | Crystal structure of S. cerevisia niemann-pick type C protein NPC2 | x-ray diffraction | A, B, C | NAG | — |
| 6R4N | Crystal structure of S. cerevisia niemann-pick type C protein NPC2 with ergosterol bound | x-ray diffraction | A, B, C, D, E, F, G, H, I | NAG, ERG, SO4 | — |
| Q12408 | AlphaFold monomer V2.0 prediction for PHOSPHATIDYLGLYCEROL/PHOSPHATIDYLINOSITOL transfer protein… | predicted | A | — | 1 (best 0.80) |
Ligands
Experiment against prediction
- 6R4M chain A against the predicted model Q12408: TM-score 0.98, RMSD 0.70 Å
- 6R4N chain A against the predicted model Q12408: TM-score 0.97, RMSD 0.75 Å
- 6R4M chain B against the predicted model Q12408: TM-score 0.97, RMSD 0.89 Å
- 6R4N chain E against the predicted model Q12408: TM-score 0.97, RMSD 0.75 Å
- 6R4N chain B against the predicted model Q12408: TM-score 0.97, RMSD 0.86 Å
- 6R4N chain D against the predicted model Q12408: TM-score 0.96, RMSD 0.93 Å
- 6R4N chain C against the predicted model Q12408: TM-score 0.94, RMSD 0.83 Å
- 6R4N chain F against the predicted model Q12408: TM-score 0.94, RMSD 1.12 Å
- 6R4N chain H against the predicted model Q12408: TM-score 0.93, RMSD 1.20 Å
- 6R4M chain C against the predicted model Q12408: TM-score 0.91, RMSD 1.01 Å
Elsewhere
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