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UniProt Q12408

PHOSPHATIDYLGLYCEROL/PHOSPHATIDYLINOSITOL transfer protein (Q12408)

PHOSPHATIDYLGLYCEROL/PHOSPHATIDYLINOSITOL transfer protein (UniProt Q12408): 2 experimental structures and 1 predicted model on GenesisL1, 3 ligands bound, 1 pocket. Binding sites, druggability and experiment against prediction…

UniProt
Q12408
Protein
PHOSPHATIDYLGLYCEROL/PHOSPHATIDYLINOSITOL transfer protein
Experimental structures
2
Predicted models
1
Ligands
3
Pockets
1 · 1 record with a druggable one

Structures

3 records of Q12408 in the MolNFT archive: 2 experimental, 1 predicted.

EntryTitleMethodChainsLigandsPockets
6R4MCrystal structure of S. cerevisia niemann-pick type C protein NPC2x-ray diffractionA, B, CNAG—
6R4NCrystal structure of S. cerevisia niemann-pick type C protein NPC2 with ergosterol boundx-ray diffractionA, B, C, D, E, F, G, H, INAG, ERG, SO4—
Q12408AlphaFold monomer V2.0 prediction for PHOSPHATIDYLGLYCEROL/PHOSPHATIDYLINOSITOL transfer protein…predictedA—1 (best 0.80)

Ligands

  • NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose · in 2 records
  • ERG · Ergosterol · in 1 record
  • SO4 · Sulfate ion · in 1 record

Experiment against prediction

Elsewhere

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