UniProt Q12386
Actin-like protein ARP8 (Q12386)
Actin-like protein ARP8 (UniProt Q12386): 8 experimental structures and 1 predicted model on GenesisL1, 3 ligands bound, 25 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q12386
- Protein
- Actin-like protein ARP8
- Experimental structures
- 8
- Predicted models
- 1
- Ligands
- 3
- Pockets
- 25 · 2 records with a druggable one
Structures
9 records of Q12386 in the MolNFT archive: 8 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 4AM6 | C-terminal domain of actin-related protein ARP8 from S. cerevisiae | x-ray diffraction | A, B | — | — |
| 4AM6 | C-terminal domain of actin-related protein ARP8 from S. cerevisiae | x-ray diffraction | A, B | — | — |
| 4AM7 | ADP-bound C-terminal domain of actin-related protein ARP8 from S. cerevisiae | x-ray diffraction | A, B | — | — |
| 4AM7 | ADP-bound C-terminal domain of actin-related protein ARP8 from S. cerevisiae | x-ray diffraction | A, B | — | — |
| 5NBN | Crystal structure of the Arp4-N-actin-Arp8-Ino80HSA module of INO80 | x-ray diffraction | E, F | — | — |
| 5NBN | Crystal structure of the ARP4-N-actin-ARP8-INO80HSA module of INO80 | x-ray diffraction | E, F | — | — |
| 8A5A | Structure of Arp4-Ies4-N-actin-Arp8-Ino80HSA subcomplex (A-module) of INO80 | electron microscopy | U | ATP, MG | 14 (best 0.87) |
| 8A5O | Structure of Arp4-Ies4-N-actin-Arp8-Ino80HSA subcomplex (A-module) of S. cerevisiae INO80 | electron microscopy | U | AGS, MG | 11 (best 0.87) |
| Q12386 | AlphaFold monomer V2.0 prediction for actin-like protein ARP8 (Q12386) | predicted | A | — | — |
Ligands
Experiment against prediction
- 5NBN chain F against the predicted model Q12386: TM-score 0.99, RMSD 0.90 Å
- 5NBN chain F against the predicted model Q12386: TM-score 0.99, RMSD 0.90 Å
- 8A5O chain U against the predicted model Q12386: TM-score 0.99, RMSD 1.16 Å
- 5NBN chain E against the predicted model Q12386: TM-score 0.99, RMSD 0.96 Å
- 5NBN chain E against the predicted model Q12386: TM-score 0.99, RMSD 0.96 Å
- 4AM6 chain A against the predicted model Q12386: TM-score 0.98, RMSD 1.13 Å
- 4AM6 chain A against the predicted model Q12386: TM-score 0.98, RMSD 1.13 Å
- 4AM7 chain A against the predicted model Q12386: TM-score 0.98, RMSD 1.14 Å
- 4AM7 chain A against the predicted model Q12386: TM-score 0.98, RMSD 1.14 Å
- 4AM6 chain B against the predicted model Q12386: TM-score 0.97, RMSD 1.37 Å
Elsewhere
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