UniProt Q12314
Protein arginine N-methyltransferase SFM1 (Q12314)
Protein arginine N-methyltransferase SFM1 (UniProt Q12314), EC 2.1.1.-: 9 experimental structures and 1 predicted model on GenesisL1, 5 ligands bound, 8 pockets. Binding sites, druggability and experiment against prediction…
- UniProt
- Q12314
- Protein
- Protein arginine N-methyltransferase SFM1
- EC
- 2.1.1.-
- Experimental structures
- 9
- Predicted models
- 1
- Ligands
- 5
- Pockets
- 8 · 5 records with a druggable one
Structures
10 records of Q12314 in the MolNFT archive: 9 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 5C74 | Structure of a novel protein arginine methyltransferase | x-ray diffraction | A, B | SO4, NI | 4 (best 0.70) |
| 5C74 | Structure of a novel protein arginine methyltransferase | x-ray diffraction | A, B | — | — |
| 5C77 | A novel protein arginine methyltransferase | x-ray diffraction | A, B | — | — |
| 5H5D | The crystal structure of the yeast arginine methyltransferase SFM1 complexed with MTA | x-ray diffraction | A | MTA | 1 (best 0.65) |
| 5H5D | The crystal structure of the yeast arginine methyltransferase SFM1 complexed with mta | x-ray diffraction | A | — | — |
| 5H5E | The crystal structure of the yeast arginine methyltransferase SFM1 complexed with SAH | x-ray diffraction | A | SAH | 1 (best 0.73) |
| 5H5E | The crystal structure of the yeast arginine methyltransferase SFM1 complexed with sah | x-ray diffraction | A | — | — |
| 5H5F | The crystal structure of the yeast arginine methyltransferase SFM1 complexed with SAM | x-ray diffraction | A | SAM | 1 (best 0.73) |
| 5H5F | The crystal structure of the yeast arginine methyltransferase SFM1 complexed with SAM | x-ray diffraction | A | — | — |
| Q12314 | AlphaFold monomer V2.0 prediction for protein arginine N-methyltransferase SFM1 (Q12314) | predicted | A | — | 1 (best 0.59) |
Ligands
Experiment against prediction
- 5H5D chain A against the predicted model Q12314: TM-score 0.97, RMSD 1.10 Å
- 5H5D chain A against the predicted model Q12314: TM-score 0.97, RMSD 1.10 Å
- 5C77 chain A against the predicted model Q12314: TM-score 0.96, RMSD 1.15 Å
- 5C77 chain B against the predicted model Q12314: TM-score 0.96, RMSD 1.18 Å
- 5C74 chain A against the predicted model Q12314: TM-score 0.95, RMSD 1.50 Å
- 5C74 chain A against the predicted model Q12314: TM-score 0.95, RMSD 1.50 Å
- 5C74 chain B against the predicted model Q12314: TM-score 0.94, RMSD 1.20 Å
- 5C74 chain B against the predicted model Q12314: TM-score 0.94, RMSD 1.20 Å
- 5H5F chain A against the predicted model Q12314: TM-score 0.88, RMSD 1.61 Å
- 5H5F chain A against the predicted model Q12314: TM-score 0.88, RMSD 1.61 Å
Elsewhere
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