UniProt Q12267
Structural maintenance of chromosomes protein 4 (Q12267)
Structural maintenance of chromosomes protein 4 (UniProt Q12267): 13 experimental structures and 1 predicted model on GenesisL1, 4 ligands bound, 49 pockets. Binding sites, druggability and experiment against prediction…
- UniProt
- Q12267
- Protein
- Structural maintenance of chromosomes protein 4
- Experimental structures
- 13
- Predicted models
- 1
- Ligands
- 4
- Pockets
- 49 · 6 records with a druggable one
Structures
14 records of Q12267 in the MolNFT archive: 13 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 4RSI | Yeast Smc2-Smc4 hinge domain with extended coiled coils | x-ray diffraction | B | — | — |
| 4RSI | Yeast SMC2-SMC4 hinge domain with extended coiled coils | x-ray diffraction | B | — | — |
| 6YVD | Head segment of the S.cerevisiae condensin holocomplex in presence of ATP | electron microscopy | D | — | 6 (best 0.81) |
| 6YVD | Head segment of the S.CEREVISIAE condensin holocomplex in presence of ATP | electron microscopy | D | — | — |
| 6YVU | Condensin complex from S.cerevisiae ATP-free apo non-engaged state | electron microscopy | B | — | 10 (best 0.81) |
| 6YVU | Condensin complex from S.CEREVISIAE ATP-free apo non-engaged state | electron microscopy | B | — | — |
| 6YVV | Condensin complex from S.cerevisiae ATP-free apo bridged state | electron microscopy | B | — | 6 (best 0.84) |
| 6YVV | Condensin complex from S.CEREVISIAE ATP-free apo bridged state | electron microscopy | B | — | — |
| 7Q2X | Cryo-EM structure of clamped S.cerevisiae condensin-DNA complex (Form I) | electron microscopy | B | ADP, BEF, MG | 9 (best 0.86) |
| 7Q2X | Cryo-EM structure of clamped S.CEREVISIAE condensin-DNA complex (form I) | electron microscopy | B | ADP, BEF, MG | — |
| 7Q2Y | Cryo-EM structure of clamped S.cerevisiae condensin-DNA complex (form II) | electron microscopy | B | ADP, BEF, MG | 9 (best 0.85) |
| 7Q2Y | Cryo-EM structure of clamped S.CEREVISIAE condensin-DNA complex (form II) | electron microscopy | B | ADP, BEF, MG | — |
| 7QEN | S.C. condensin core in DNA- and ATP-bound state | electron microscopy | B | ATP, MG | — |
| Q12267 | AlphaFold monomer V2.0 prediction for structural maintenance of chromosomes protein 4 (Q12267) | predicted | A | — | 9 (best 0.64) |
Ligands
Experiment against prediction
- 7Q2X chain B against the predicted model Q12267: TM-score 0.93, RMSD 1.97 Å
- 7Q2X chain B against the predicted model Q12267: TM-score 0.93, RMSD 1.97 Å
- 7QEN chain B against the predicted model Q12267: TM-score 0.92, RMSD 2.16 Å
- 7Q2Y chain B against the predicted model Q12267: TM-score 0.92, RMSD 2.44 Å
- 7Q2Y chain B against the predicted model Q12267: TM-score 0.92, RMSD 2.44 Å
- 6YVV chain B against the predicted model Q12267: TM-score 0.86, RMSD 3.55 Å
- 6YVV chain B against the predicted model Q12267: TM-score 0.86, RMSD 3.55 Å
- 6YVD chain D against the predicted model Q12267: TM-score 0.81, RMSD 3.73 Å
- 6YVD chain D against the predicted model Q12267: TM-score 0.81, RMSD 3.73 Å
- 4RSI chain B against the predicted model Q12267: TM-score 0.76, RMSD 4.43 Å
Elsewhere
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