UniProt Q12154
ATPase GET3 (Q12154)
ATPase GET3 (UniProt Q12154), EC 3.6.-.-: 30 experimental structures and 1 predicted model on GenesisL1, 3 ligands bound, 13 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q12154
- Protein
- ATPase GET3
- EC
- 3.6.-.-
- Experimental structures
- 30
- Predicted models
- 1
- Ligands
- 3
- Pockets
- 13 · 1 record with a druggable one
Structures
31 records of Q12154 in the MolNFT archive: 30 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2WOJ | ADP-AlF4 complex of S. cerevisiae GET3 | x-ray diffraction | A, B, C, D | — | — |
| 2WOJ | ADP-ALF4 complex of S. cerevisiae GET3 | x-ray diffraction | A, B, C, D | — | — |
| 3A36 | Structural insight into the membrane insertion of tail-anchored proteins by Get3 | x-ray diffraction | A, B | — | — |
| 3A36 | Structural insight into the membrane insertion of tail- anchored proteins by GET3 | x-ray diffraction | A, B | — | — |
| 3A37 | Structural insight into the membrane insertion of tail-anchored proteins by Get3 | x-ray diffraction | A, B | — | — |
| 3A37 | Structural insight into the membrane insertion of tail-anchored proteins by GET3 | x-ray diffraction | A, B | — | — |
| 3H84 | Crystal structure of GET3 | x-ray diffraction | A, B | — | — |
| 3H84 | Crystal structure of GET3 | x-ray diffraction | A, B | — | — |
| 3IDQ | Crystal structure of S. cerevisiae Get3 at 3.7 Angstrom resolution | x-ray diffraction | A | — | — |
| 3IDQ | Crystal structure of S. cerevisiae GET3 at 3.7 ångström resolution | x-ray diffraction | A | — | — |
| 3SJA | Crystal structure of S. cerevisiae Get3 in the open state in complex with Get1 cytosolic domain | x-ray diffraction | A, B, E, F, I | — | — |
| 3SJA | Crystal structure of S. cerevisiae GET3 in the open state in complex with GET1 cytosolic domain | x-ray diffraction | A, B, E, F, I | — | — |
| 3SJB | Crystal structure of S. cerevisiae Get3 in the open state in complex with Get1 cytosolic domain | x-ray diffraction | A, B | — | — |
| 3SJB | Crystal structure of S. cerevisiae GET3 in the open state in complex with GET1 cytosolic domain | x-ray diffraction | A, B | — | — |
| 3SJC | Crystal structure of S.cerevisiae Get3 in the semi-open state in complex with Get1 cytosolic domain | x-ray diffraction | A, B, E, F | — | — |
| 3SJC | Crystal structure of S.CEREVISIAE GET3 in the semi-open state in complex with GET1 cytosolic domain | x-ray diffraction | A, B, E, F | — | — |
| 3SJD | Crystal structure of S. cerevisiae Get3 with bound ADP-Mg2+ in complex with Get2 cytosolic domain | x-ray diffraction | A, B, C | — | — |
| 3SJD | Crystal structure of S. cerevisiae GET3 with bound ADP-MG2+ in complex with GET2 cytosolic domain | x-ray diffraction | A, B, C | — | — |
| 3ZS8 | S. cerevisiae Get3 complexed with a cytosolic Get1 fragment | x-ray diffraction | A, B | — | — |
| 3ZS8 | S. cerevisiae GET3 complexed with a cytosolic GET1 fragment | x-ray diffraction | A, B | — | — |
| 3ZS9 | S. cerevisiae Get3-ADP-AlF4- complex with a cytosolic Get2 fragment | x-ray diffraction | A, B | — | — |
| 3ZS9 | S. cerevisiae GET3-ADP-ALF4- complex with a cytosolic GET2 fragment | x-ray diffraction | A, B | — | — |
| 4PWX | Crystal structure of an ATP-bound Get3-Get4-Get5 complex from S.cerevisiae | x-ray diffraction | A, B | — | — |
| 4PWX | Crystal structure of an ATP-bound GET3-GET4-GET5 complex from S.CEREVISIAE | x-ray diffraction | A, B | — | — |
| 4XTR | Structure of Get3 bound to the transmembrane domain of Pep12 | x-ray diffraction | A, B | — | — |
| 4XTR | Structure of GET3 bound to the transmembrane domain of PEP12 | x-ray diffraction | A, B | — | — |
| 4XVU | Structure of Get3 bound to the transmembrane domain of Nyv1 | x-ray diffraction | A, B, G, H | ATP, MG, ZN | 13 (best 0.88) |
| 4XVU | Structure of GET3 bound to the transmembrane domain of NYV1 | x-ray diffraction | A, B, G, H | — | — |
| 4XWO | Structure of Get3 bound to the transmembrane domain of Sec22 | x-ray diffraction | A, B, G, H, M, N, S, T | — | — |
| 4XWO | Structure of GET3 bound to the transmembrane domain of SEC22 | x-ray diffraction | A, B, G, H, M, N, S, T | — | — |
| Q12154 | AlphaFold monomer V2.0 prediction for ATPase GET3 (Q12154) | predicted | A | — | — |
Ligands
Experiment against prediction
- 4XWO chain G against the predicted model Q12154: TM-score 0.97, RMSD 1.10 Å
- 4XWO chain G against the predicted model Q12154: TM-score 0.97, RMSD 1.10 Å
- 4XWO chain S against the predicted model Q12154: TM-score 0.97, RMSD 1.14 Å
- 4XWO chain S against the predicted model Q12154: TM-score 0.97, RMSD 1.14 Å
- 4XWO chain N against the predicted model Q12154: TM-score 0.97, RMSD 1.16 Å
- 4XWO chain N against the predicted model Q12154: TM-score 0.97, RMSD 1.16 Å
- 2WOJ chain C against the predicted model Q12154: TM-score 0.97, RMSD 1.16 Å
- 2WOJ chain C against the predicted model Q12154: TM-score 0.97, RMSD 1.16 Å
- 4XWO chain H against the predicted model Q12154: TM-score 0.97, RMSD 1.20 Å
- 4XWO chain H against the predicted model Q12154: TM-score 0.97, RMSD 1.20 Å
Elsewhere
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