UniProt Q12051
Q12051
Q12051 (UniProt Q12051): 48 experimental structures and 1 predicted model on GenesisL1. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q12051
- Experimental structures
- 48
- Predicted models
- 1
Structures
49 records of Q12051 in the MolNFT archive: 48 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2DH4 | Geranylgeranyl pyrophosphate synthase | x-ray diffraction | A, B | — | — |
| 2DH4 | Geranylgeranyl pyrophosphate synthase | x-ray diffraction | A, B | — | — |
| 2E8T | S. cerevisiae geranylgeranyl pyrophosphate synthase in complex with magnesium, FsPP and IPP | x-ray diffraction | A, B | — | — |
| 2E8T | S. cerevisiae geranylgeranyl pyrophosphate synthase in complex with magnesium, fspp and ipp | x-ray diffraction | A, B | — | — |
| 2E8U | S. cerevisiae geranylgeranyl pyrophosphate synthase in complex with magnesium and IPP (P21) | x-ray diffraction | A, B | — | — |
| 2E8U | S. cerevisiae geranylgeranyl pyrophosphate synthase in complex with magnesium and ipp (P21) | x-ray diffraction | A, B | — | — |
| 2E8V | S. cerevisiae geranylgeranyl pyrophosphate synthase in complex with product GGPP (P21) | x-ray diffraction | A, B | — | — |
| 2E8V | S. cerevisiae geranylgeranyl pyrophosphate synthase in complex with product ggpp (P21) | x-ray diffraction | A, B | — | — |
| 2E8W | S. cerevisiae geranylgeranyl pyrophosphate synthase in complex with magnesium and IPP | x-ray diffraction | A, B | — | — |
| 2E8W | S. cerevisiae geranylgeranyl pyrophosphate synthase in complex with magnesium and ipp | x-ray diffraction | A, B | — | — |
| 2E8X | S. cerevisiae geranylgeranyl pyrophosphate synthase in complex with magnesium and GPP | x-ray diffraction | A, B | — | — |
| 2E8X | S. cerevisiae geranylgeranyl pyrophosphate synthase in complex with magnesium and gpp | x-ray diffraction | A, B | — | — |
| 2E90 | S. cerevisiae geranylgeranyl pyrophosphate synthase in complex with magnesium, pyrophosphate and FPP | x-ray diffraction | A, B | — | — |
| 2E90 | S. cerevisiae geranylgeranyl pyrophosphate synthase in complex with magnesium, pyrophosphate and fpp | x-ray diffraction | A, B | — | — |
| 2E91 | S. cerevisiae geranylgeranyl pyrophosphate synthase in complex with magnesium and BPH-91 | x-ray diffraction | A, B | — | — |
| 2E91 | S. cerevisiae geranylgeranyl pyrophosphate synthase in complex with magnesium and bph-91 | x-ray diffraction | A, B | — | — |
| 2E92 | S. cerevisiae geranylgeranyl pyrophosphate synthase in complex with magnesium and BPH-261 | x-ray diffraction | A, B | — | — |
| 2E92 | S. cerevisiae geranylgeranyl pyrophosphate synthase in complex with magnesium and bph-261 | x-ray diffraction | A, B | — | — |
| 2E93 | S. cerevisiae geranylgeranyl pyrophosphate synthase in complex with BPH-629 | x-ray diffraction | A, B | — | — |
| 2E93 | S. cerevisiae geranylgeranyl pyrophosphate synthase in complex with bph-629 | x-ray diffraction | A, B | — | — |
| 2E94 | S. cerevisiae geranylgeranyl pyrophosphate synthase in complex with magnesium and BPH-364 | x-ray diffraction | A, B | — | — |
| 2E94 | S. cerevisiae geranylgeranyl pyrophosphate synthase in complex with magnesium and bph-364 | x-ray diffraction | A, B | — | — |
| 2E95 | S. cerevisiae geranylgeranyl pyrophosphate synthase in complex with magnesium and BPH-675 | x-ray diffraction | A, B | — | — |
| 2E95 | S. cerevisiae geranylgeranyl pyrophosphate synthase in complex with magnesium and bph-675 | x-ray diffraction | A, B | — | — |
| 2Z4V | S. cerevisiae geranylgeranyl pyrophosphate synthase in complex with magnesium and GGPP (inhibitory… | x-ray diffraction | A, B | — | — |
| 2Z4V | S. cerevisiae geranylgeranyl pyrophosphate synthase in complex with magnesium and ggpp (inhibitory… | x-ray diffraction | A, B | — | — |
| 2Z4W | S. cerevisiae geranylgeranyl pyrophosphate synthase in complex with magnesium and BPH-749 | x-ray diffraction | A, B | — | — |
| 2Z4W | S. cerevisiae geranylgeranyl pyrophosphate synthase in complex with magnesium and bph-749 | x-ray diffraction | A, B | — | — |
| 2Z4X | S. cerevisiae geranylgeranyl pyrophosphate synthase in complex with magnesium and BPH-252 (P21) | x-ray diffraction | A, B | — | — |
| 2Z4X | S. cerevisiae geranylgeranyl pyrophosphate synthase in complex with magnesium and bph-252 (P21) | x-ray diffraction | A, B | — | — |
| 2Z4Y | S. cerevisiae geranylgeranyl pyrophosphate synthase in complex with magnesium and BPH-252 | x-ray diffraction | A, B | — | — |
| 2Z4Y | S. cerevisiae geranylgeranyl pyrophosphate synthase in complex with magnesium and bph-252 | x-ray diffraction | A, B | — | — |
| 2Z4Z | S. cerevisiae geranylgeranyl pyrophosphate synthase in complex with magnesium and BPH-sc01 | x-ray diffraction | A, B | — | — |
| 2Z4Z | S. cerevisiae geranylgeranyl pyrophosphate synthase in complex with magnesium and bph-SC01 | x-ray diffraction | A, B | — | — |
| 2Z50 | S. cerevisiae geranylgeranyl pyrophosphate synthase in complex with BPH-28 | x-ray diffraction | A, B | — | — |
| 2Z50 | S. cerevisiae geranylgeranyl pyrophosphate synthase in complex with bph-28 | x-ray diffraction | A, B | — | — |
| 2Z52 | S. cerevisiae geranylgeranyl pyrophosphate synthase in complex with magnesium and BPH-23 | x-ray diffraction | A, B | — | — |
| 2Z52 | S. cerevisiae geranylgeranyl pyrophosphate synthase in complex with magnesium and bph-23 | x-ray diffraction | A, B | — | — |
| 2Z78 | S. cerevisiae geranylgeranyl pyrophosphate synthase in complex with BPH-806 | x-ray diffraction | A, B | — | — |
| 2Z78 | S. cerevisiae geranylgeranyl pyrophosphate synthase in complex with bph-806 | x-ray diffraction | A, B | — | — |
| 2Z7H | S. cerevisiae geranylgeranyl pyrophosphate synthase in complex with inhibitor BPH-210 | x-ray diffraction | A, B | — | — |
| 2Z7H | S. cerevisiae geranylgeranyl pyrophosphate synthase in complex with inhibitor bph-210 | x-ray diffraction | A, B | — | — |
| 2Z7I | S. cerevisiae geranylgeranyl pyrophosphate synthase in complex with inhibitor BPH-742 | x-ray diffraction | A, B | — | — |
| 2Z7I | S. cerevisiae geranylgeranyl pyrophosphate synthase in complex with inhibitor bph-742 | x-ray diffraction | A, B | — | — |
| 2ZEU | S. Cerevisiae Geranylgeranyl Pyrophosphate Synthase in Complex with BPH-715 | x-ray diffraction | A, B | — | — |
| 2ZEU | S. cerevisiae geranylgeranyl pyrophosphate synthase in complex with bph-715 | x-ray diffraction | A, B | — | — |
| 2ZEV | S. Cerevisiae Geranylgeranyl Pyrophosphate Synthase in Complex with Magnesium, IPP and BPH-715 | x-ray diffraction | A, B | — | — |
| 2ZEV | S. cerevisiae geranylgeranyl pyrophosphate synthase in complex with magnesium, ipp and bph-715 | x-ray diffraction | A, B | — | — |
| Q12051 | AlphaFold monomer V2.0 prediction for geranylgeranyl pyrophosphate synthase (Q12051) | predicted | A | — | — |
Experiment against prediction
- 2E8V chain B against the predicted model Q12051: TM-score 0.99, RMSD 0.61 Å
- 2E8V chain B against the predicted model Q12051: TM-score 0.99, RMSD 0.61 Å
- 2E8V chain A against the predicted model Q12051: TM-score 0.99, RMSD 0.65 Å
- 2E8V chain A against the predicted model Q12051: TM-score 0.99, RMSD 0.65 Å
- 2E8U chain B against the predicted model Q12051: TM-score 0.99, RMSD 0.94 Å
- 2E8U chain B against the predicted model Q12051: TM-score 0.99, RMSD 0.94 Å
- 2Z4X chain B against the predicted model Q12051: TM-score 0.99, RMSD 0.95 Å
- 2Z4X chain B against the predicted model Q12051: TM-score 0.99, RMSD 0.95 Å
- 2E91 chain B against the predicted model Q12051: TM-score 0.98, RMSD 0.85 Å
- 2E91 chain B against the predicted model Q12051: TM-score 0.98, RMSD 0.85 Å
Elsewhere
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