UniProt Q12001
Dolichyl pyrophosphate Man9GlcNAc2 alpha-1,3-glucosyltransferase (Q12001)
Dolichyl pyrophosphate Man9GlcNAc2 alpha-1,3-glucosyltransferase (UniProt Q12001), EC 2.4.1.267: 4 experimental structures and 1 predicted model on GenesisL1, 3 ligands bound, 16 pockets. Binding sites, druggability and…
- UniProt
- Q12001
- Protein
- Dolichyl pyrophosphate Man9GlcNAc2 alpha-1,3-glucosyltransferase
- EC
- 2.4.1.267
- Experimental structures
- 4
- Predicted models
- 1
- Ligands
- 3
- Pockets
- 16 · 2 records with a druggable one
Structures
5 records of Q12001 in the MolNFT archive: 4 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 6SNH | Cryo-EM structure of yeast ALG6 in complex with 6AG9 Fab and Dol25-P-Glc | electron microscopy | X | LMH | 9 (best 0.76) |
| 6SNH | Cryo-EM structure of yeast ALG6 in complex with 6AG9 Fab and DOL25-P- glc | electron microscopy | X | LMH | — |
| 6SNI | Cryo-EM structure of nanodisc reconstituted yeast ALG6 in complex with 6AG9 Fab | electron microscopy | X | PTY, Y01 | 7 (best 0.76) |
| 6SNI | Cryo-EM structure of nanodisc reconstituted yeast ALG6 in complex with 6AG9 Fab | electron microscopy | X | PTY, Y01 | — |
| Q12001 | AlphaFold monomer V2.0 prediction for dolichyl pyrophosphate MAN9GLCNAC2… | predicted | A | — | — |
Ligands
Experiment against prediction
- 6SNI chain X against the predicted model Q12001: TM-score 0.98, RMSD 1.15 Å
- 6SNI chain X against the predicted model Q12001: TM-score 0.98, RMSD 1.15 Å
- 6SNH chain X against the predicted model Q12001: TM-score 0.98, RMSD 1.21 Å
- 6SNH chain X against the predicted model Q12001: TM-score 0.98, RMSD 1.21 Å
Elsewhere
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