UniProt Q10QA5
Strigolactone esterase D14 (Q10QA5)
Strigolactone esterase D14 (UniProt Q10QA5), EC 3.1.-.-: 27 experimental structures and 1 predicted model on GenesisL1, 6 ligands bound, 20 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q10QA5
- Protein
- Strigolactone esterase D14
- EC
- 3.1.-.-
- Experimental structures
- 27
- Predicted models
- 1
- Ligands
- 6
- Pockets
- 20 · 6 records with a druggable one
Structures
28 records of Q10QA5 in the MolNFT archive: 27 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 3VXK | Crystal structure of OsD14 | x-ray diffraction | A, B | — | — |
| 3VXK | Crystal structure of OSD14 | x-ray diffraction | A, B | — | — |
| 3W04 | Crystal structure of Oryza sativa DWARF14 (D14) | x-ray diffraction | A, B | — | — |
| 3W04 | Crystal structure of oryza sativa DWARF14 (D14) | x-ray diffraction | A, B | — | — |
| 3W05 | Crystal structure of Oryza sativa DWARF14 (D14) in complex with PMSF | x-ray diffraction | A, B | — | — |
| 3W05 | Crystal structure of oryza sativa DWARF14 (D14) in complex with pmsf | x-ray diffraction | A, B | — | — |
| 3WIO | Crystal structure of OSD14 in complex with hydroxy D-ring | x-ray diffraction | A, B | — | — |
| 3WIO | Crystal structure of OSD14 in complex with hydroxy D-ring | x-ray diffraction | A, B | — | — |
| 4IH9 | Crystal structure of rice DWARF14 (D14) | x-ray diffraction | A, B | — | — |
| 4IH9 | Crystal structure of rice DWARF14 (D14) | x-ray diffraction | A, B | — | — |
| 4IHA | Crystal structure of rice DWARF14 (D14) in complex with a GR24 hydrolysis intermediate | x-ray diffraction | A, B | — | — |
| 4IHA | Crystal structure of rice DWARF14 (D14) in complex with a GR24 hydrolysis intermediate | x-ray diffraction | A, B | — | — |
| 5DJ5 | Crystal structure of rice DWARF14 in complex with synthetic strigolactone GR24 | x-ray diffraction | A, B | GR2 | — |
| 5DJ5 | Crystal structure of rice DWARF14 in complex with synthetic strigolactone GR24 | x-ray diffraction | A, B | — | — |
| 5YZ7 | Crystal structure of OsD14 in complex with D-ring-opened 7'-carba-4BD | x-ray diffraction | A, B | 94X | — |
| 5YZ7 | Crystal structure of OSD14 in complex with D-ring-opened 7'-carba-4BD | x-ray diffraction | A, B | 94X | — |
| 5ZHR | Crystal structure of OsD14 in complex with covalently bound KK094 | x-ray diffraction | A, B | KOK | 4 (best 0.68) |
| 5ZHR | Crystal structure of OSD14 in complex with covalently bound KK094 | x-ray diffraction | A, B | KOK | — |
| 5ZHS | Crystal structure of OsD14 in complex with covalently bound KK052 | x-ray diffraction | A | KAT | 1 (best 0.64) |
| 5ZHS | Crystal structure of OSD14 in complex with covalently bound KK052 | x-ray diffraction | A | KAT | — |
| 5ZHT | Crystal structure of OsD14 in complex with covalently bound KK073 | x-ray diffraction | A | 9GU | 1 (best 0.67) |
| 5ZHT | Crystal structure of OSD14 in complex with covalently bound KK073 | x-ray diffraction | A | 9GU | — |
| 6AP8 | Crystal Structure of rice D14 bound to 2-(2-methyl-3-nitroanilino)benzoic acid | x-ray diffraction | A, B | BNY | 5 (best 0.71) |
| 6AP8 | Crystal structure of rice D14 bound to 2-(2-methyl-3-nitroanilino) benzoic acid | x-ray diffraction | A, B | BNY | — |
| 6ELX | Oryza sativa DWARF14 | x-ray diffraction | A, B | — | 5 (best 0.69) |
| 6ELX | Oryza sativa DWARF14 | x-ray diffraction | A, B | — | — |
| 8IF6 | Conformational Dynamics of the D53-D3-D14 Complex in Strigolactone Signaling | electron microscopy | C | — | 4 (best 0.76) |
| Q10QA5 | AlphaFold monomer V2.0 prediction for strigolactone esterase D14 (Q10QA5) | predicted | A | — | — |
Ligands
- 94X · (2Z,4S)-5-(4-bromophenyl)-4-hydroxy-2-methylpent-2-enoic acid · in 2 records
- 9GU · (1H-1,2,3-triazol-1-yl){4-[4-(trifluoromethyl) phenyl]piperazin-1-yl}methanone · in 2 records
- BNY · 2-[(2-methyl-3-nitrophenyl)amino]benzoic acid · in 2 records
- KAT · (4-phenylpiperazin-1-yl)(1h-1,2,3-triazol-1-yl) methanone · in 2 records
- KOK · (2,3-dihydro-1H-indol-1-yl)(1h-1,2,3-triazol-1-yl) methanone · in 2 records
- GR2 · (3E,3aR,8bS)-3-({[(2R)-4-methyl-5-oxo-2,5-dihydrofuran-2-yl]oxy}methylidene)-3,3a,4,8b-tetrahydro-2H-indeno[1,2-b]furan-2-one · in 1 record
Experiment against prediction
- 3W04 chain A against the predicted model Q10QA5: TM-score 1.00, RMSD 0.25 Å
- 3W04 chain A against the predicted model Q10QA5: TM-score 1.00, RMSD 0.25 Å
- 4IH9 chain A against the predicted model Q10QA5: TM-score 1.00, RMSD 0.27 Å
- 4IH9 chain A against the predicted model Q10QA5: TM-score 1.00, RMSD 0.27 Å
- 5ZHR chain B against the predicted model Q10QA5: TM-score 1.00, RMSD 0.27 Å
- 5ZHR chain B against the predicted model Q10QA5: TM-score 1.00, RMSD 0.27 Å
- 6AP8 chain A against the predicted model Q10QA5: TM-score 1.00, RMSD 0.28 Å
- 6AP8 chain A against the predicted model Q10QA5: TM-score 1.00, RMSD 0.28 Å
- 3VXK chain B against the predicted model Q10QA5: TM-score 1.00, RMSD 0.28 Å
- 3VXK chain B against the predicted model Q10QA5: TM-score 1.00, RMSD 0.28 Å
Elsewhere
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