UniProt Q10469
Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase (Q10469)
Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase (UniProt Q10469), EC 2.4.1.143: 4 experimental structures and 1 predicted model on GenesisL1, 7 ligands bound, 9 pockets. Binding sites, druggability and…
- UniProt
- Q10469
- Protein
- Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase
- EC
- 2.4.1.143
- Experimental structures
- 4
- Predicted models
- 1
- Ligands
- 7
- Pockets
- 9 · 1 record with a druggable one
Structures
5 records of Q10469 in the MolNFT archive: 4 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 5VCM | Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase with bound udp and manganese | x-ray diffraction | A, B | MN, UDP, NAG | — |
| 5VCR | Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase with bound uranium dioxide | x-ray diffraction | A, B | IUM, NAG, CL | — |
| 5VCS | Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase with Bound Acceptor | x-ray diffraction | A, B | NAG, BMA, MAN | 9 (best 0.81) |
| 5VCS | Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase with bound acceptor | x-ray diffraction | A, B | NAG, BMA, MAN | — |
| Q10469 | AlphaFold monomer V2.0 prediction for alpha-1,6-mannosyl-glycoprotein… | predicted | A | — | — |
Ligands
Experiment against prediction
- 5VCM chain A against the predicted model Q10469: TM-score 0.99, RMSD 0.53 Å
- 5VCR chain B against the predicted model Q10469: TM-score 0.99, RMSD 0.75 Å
- 5VCS chain B against the predicted model Q10469: TM-score 0.99, RMSD 0.82 Å
- 5VCS chain B against the predicted model Q10469: TM-score 0.99, RMSD 0.82 Å
- 5VCR chain A against the predicted model Q10469: TM-score 0.98, RMSD 1.08 Å
- 5VCS chain A against the predicted model Q10469: TM-score 0.98, RMSD 1.15 Å
- 5VCS chain A against the predicted model Q10469: TM-score 0.98, RMSD 1.15 Å
- 5VCM chain B against the predicted model Q10469: TM-score 0.96, RMSD 1.57 Å
Elsewhere
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