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UniProt Q0VBL6

Hypoxia-inducible factor 3-alpha (Q0VBL6)

Hypoxia-inducible factor 3-alpha (UniProt Q0VBL6): 4 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 16 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.

UniProt
Q0VBL6
Protein
Hypoxia-inducible factor 3-alpha
Experimental structures
4
Predicted models
1
Ligands
1
Pockets
16 · 2 records with a druggable one

Structures

5 records of Q0VBL6 in the MolNFT archive: 4 experimental, 1 predicted.

EntryTitleMethodChainsLigandsPockets
7V7LCrystal Structure of the Heterodimeric HIF-3a:ARNT Complexx-ray diffractionB—10 (best 0.72)
7V7LCrystal structure of the heterodimeric hif-3A:ARNT complexx-ray diffractionB——
7V7WCrystal Structure of the Heterodimeric HIF-3a:ARNT Complex with oleoylethanolamide (OEA)x-ray diffractionB5YM6 (best 0.71)
7V7WCrystal structure of the heterodimeric hif-3A:ARNT complex with oleoylethanolamide (oea)x-ray diffractionB5YM—
Q0VBL6AlphaFold monomer V2.0 prediction for hypoxia-inducible factor 3-alpha (Q0VBL6)predictedA——

Ligands

  • 5YM · (Z)-N-(2-hydroxyethyl)octadec-9-enamide · in 2 records

Experiment against prediction

Elsewhere

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