UniProt Q0PA35
Bifunctional protein FolD (Q0PA35)
Bifunctional protein FolD (UniProt Q0PA35), EC 1.5.1.5, 3.5.4.9: 6 experimental structures and 1 predicted model on GenesisL1, 5 ligands bound, 8 pockets. Binding sites, druggability and experiment against prediction (TM-score)…
- UniProt
- Q0PA35
- Protein
- Bifunctional protein FolD
- EC
- 1.5.1.5, 3.5.4.9
- Experimental structures
- 6
- Predicted models
- 1
- Ligands
- 5
- Pockets
- 8 · 2 records with a druggable one
Structures
7 records of Q0PA35 in the MolNFT archive: 6 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 3P2O | Crystal Structure of FolD Bifunctional Protein from Campylobacter jejuni | x-ray diffraction | A, B | — | — |
| 3P2O | Crystal structure of fold bifunctional protein from campylobacter jejuni | x-ray diffraction | A, B | — | — |
| 6DE8 | Crystal Structure of Bifunctional Enzyme FolD-Methylenetetrahydrofolate… | x-ray diffraction | A, B | IOD, CL, K | 4 (best 0.74) |
| 6DE8 | Crystal structure of bifunctional enzyme fold- methylenetetrahydrofolate… | x-ray diffraction | A, B | IOD, CL, K | — |
| 6DEB | Crystal Structure of Bifunctional Enzyme FolD-Methylenetetrahydrofolate… | x-ray diffraction | A, B | GUN, K, CL, MTX | 4 (best 0.74) |
| 6DEB | Crystal structure of bifunctional enzyme fold- methylenetetrahydrofolate… | x-ray diffraction | A, B | GUN, K, CL | — |
| Q0PA35 | AlphaFold monomer V2.0 prediction for bifunctional protein fold (Q0PA35) | predicted | A | — | — |
Ligands
Experiment against prediction
- 6DEB chain B against the predicted model Q0PA35: TM-score 0.99, RMSD 0.55 Å
- 6DEB chain B against the predicted model Q0PA35: TM-score 0.98, RMSD 0.55 Å
- 6DE8 chain A against the predicted model Q0PA35: TM-score 0.99, RMSD 0.53 Å
- 6DE8 chain A against the predicted model Q0PA35: TM-score 0.99, RMSD 0.53 Å
- 6DEB chain A against the predicted model Q0PA35: TM-score 0.98, RMSD 0.75 Å
- 6DEB chain A against the predicted model Q0PA35: TM-score 0.98, RMSD 0.75 Å
- 3P2O chain A against the predicted model Q0PA35: TM-score 0.98, RMSD 0.66 Å
- 3P2O chain A against the predicted model Q0PA35: TM-score 0.98, RMSD 0.66 Å
- 6DE8 chain B against the predicted model Q0PA35: TM-score 0.98, RMSD 0.74 Å
- 6DE8 chain B against the predicted model Q0PA35: TM-score 0.98, RMSD 0.74 Å
Elsewhere
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