UniProt Q0JRZ9
AP-2 complex subunit mu,F-BAR domain only protein 2 (Q0JRZ9)
AP-2 complex subunit mu,F-BAR domain only protein 2 (UniProt Q0JRZ9): 8 experimental structures and 1 predicted model on GenesisL1, 29 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q0JRZ9
- Protein
- AP-2 complex subunit mu,F-BAR domain only protein 2
- Experimental structures
- 8
- Predicted models
- 1
- Pockets
- 29 · 6 records with a druggable one
Structures
9 records of Q0JRZ9 in the MolNFT archive: 8 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 7OG1 | AP2 clathrin adaptor core in complex with cargo peptide and FCHO2 | x-ray diffraction | GGG, DDD | — | 2 (best 0.75) |
| 7OHO | Crystal structure of AP2 FCHO2 chimera | x-ray diffraction | BBB | — | 9 (best 0.85) |
| 7OHZ | Crystal structure of AP2 Mu2 - FCHO2 chimera (His6-tagged) | x-ray diffraction | B, A | — | 5 (best 0.78) |
| 7OHZ | Crystal structure of AP2 MU2 - FCHO2 chimera (HIS6-tagged) | x-ray diffraction | B, A | — | 5 (best 0.78) |
| 7OI5 | Crystal structure of AP2 Mu2 - FCHO2 chimera (GST cleaved) | x-ray diffraction | B, D | — | 3 (best 0.77) |
| 7OI5 | Crystal structure of AP2 MU2 - FCHO2 chimera (GST cleaved) | x-ray diffraction | B, D | — | 3 (best 0.77) |
| 7OIQ | Crystal structure of AP2 Mu2 in complex with FCHO2 WxxPhi motif (C2 crystal form) | x-ray diffraction | CCC, DDD | — | 1 (best 0.28) |
| 7OIT | Crystal structure of AP2 Mu2 in complex with FCHO2 WxxPhi motif (P3221 crystal form) | x-ray diffraction | BBB | — | 1 (best 0.41) |
| Q0JRZ9 | AlphaFold monomer V2.0 prediction for F-bar domain only protein 2 (Q0JRZ9) | predicted | A | — | — |
Experiment against prediction
- 7OHO chain BBB against the predicted model P63010: TM-score 0.91, RMSD 2.07 Å
- 7OI5 chain D against the predicted model P84092: TM-score 0.87, RMSD 1.71 Å
- 7OI5 chain D against the predicted model P84092: TM-score 0.87, RMSD 1.71 Å
- 7OHZ chain A against the predicted model P84092: TM-score 0.86, RMSD 1.76 Å
- 7OHZ chain A against the predicted model P84092: TM-score 0.86, RMSD 1.76 Å
- 7OI5 chain B against the predicted model P84092: TM-score 0.86, RMSD 1.83 Å
- 7OI5 chain B against the predicted model P84092: TM-score 0.86, RMSD 1.83 Å
- 7OHZ chain B against the predicted model P84092: TM-score 0.85, RMSD 1.91 Å
- 7OHZ chain B against the predicted model P84092: TM-score 0.85, RMSD 1.91 Å
- 7OI5 chain D against the predicted model Q0JRZ9: TM-score 0.70, RMSD 2.99 Å
Elsewhere
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