UniProt Q09328
Alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase A (Q09328)
Alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase A (UniProt Q09328), EC 2.4.1.155: 8 experimental structures and 1 predicted model on GenesisL1, 6 ligands bound, 15 pockets. Binding sites, druggability and…
- UniProt
- Q09328
- Protein
- Alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase A
- EC
- 2.4.1.155
- Experimental structures
- 8
- Predicted models
- 1
- Ligands
- 6
- Pockets
- 15 · 1 record with a druggable one
Structures
9 records of Q09328 in the MolNFT archive: 8 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 5ZIB | Crystal structure of human gnt-V luminal domain in apo form | x-ray diffraction | A | NAG | — |
| 5ZIC | Crystal structure of human gnt-V luminal domain in complex with acceptor sugar | x-ray diffraction | A, B | BMA, Z4Y, NAG | — |
| 6YJS | Crystal structure of MGAT5 (alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase… | x-ray diffraction | AAA, BBB | MAN, NAG, SO4 | — |
| 6YJU | Crystal structure of MGAT5 (alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase… | x-ray diffraction | AAA, BBB | MAN, NAG, UDP, SO4 | 15 (best 0.83) |
| 7YYI | Solution NMR structure of N-acetylglucosaminyltransferase V (GnTV) TMD | solution nmr | A | — | — |
| 7Z07 | Solution NMR structure of N-acetylglucosaminyltransferase V (GnTV) G26P mutant TMD | solution nmr | A | — | — |
| 7Z08 | Solution NMR structure of N-acetylglucosaminyltransferase V (GnTV) G22L mutant TMD | solution nmr | A | — | — |
| 7Z0B | Solution NMR structure of N-acetylglucosaminyltransferase V (GnTV) G22L and G26L double mutant TMD | solution nmr | A | — | — |
| Q09328 | AlphaFold monomer V2.0 prediction for alpha-1,6-mannosylglycoprotein… | predicted | A | — | — |
Ligands
Experiment against prediction
- 5ZIC chain A against the predicted model Q09328: TM-score 0.98, RMSD 1.14 Å
- 6YJS chain AAA against the predicted model Q09328: TM-score 0.98, RMSD 1.28 Å
- 5ZIC chain B against the predicted model Q09328: TM-score 0.97, RMSD 1.37 Å
- 6YJU chain AAA against the predicted model Q09328: TM-score 0.97, RMSD 1.43 Å
- 6YJU chain BBB against the predicted model Q09328: TM-score 0.97, RMSD 1.50 Å
- 6YJS chain BBB against the predicted model Q09328: TM-score 0.96, RMSD 1.59 Å
- 5ZIB chain A against the predicted model Q09328: TM-score 0.91, RMSD 3.15 Å
- 7Z0B chain A against the predicted model Q09328: TM-score 0.65, RMSD 1.43 Å
- 7Z07 chain A against the predicted model Q09328: TM-score 0.61, RMSD 1.01 Å
- 7YYI chain A against the predicted model Q09328: TM-score 0.52, RMSD 1.89 Å
Elsewhere
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