UniProt Q09176
Splicing factor U2AF 23 kDa subunit (Q09176)
Splicing factor U2AF 23 kDa subunit (UniProt Q09176): 8 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 128 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q09176
- Protein
- Splicing factor U2AF 23 kDa subunit
- Experimental structures
- 8
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 128 · 8 records with a druggable one
Structures
9 records of Q09176 in the MolNFT archive: 8 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 4YH8 | Structure of yeast U2AF complex | x-ray diffraction | A | ZN | 3 (best 0.62) |
| 4YH8 | Structure of yeast U2AF complex | x-ray diffraction | A | ZN | 3 (best 0.62) |
| 7C06 | Crystal structure of yeast U2AF1 complex bound to 3' splice site RNA, 5'-UAGGU. | x-ray diffraction | A, D, G, J, M, P, S, V, Y | ZN | 20 (best 0.87) |
| 7C06 | Crystal structure of yeast U2AF1 complex bound to 3' splice site RNA, 5'-uaggu. | x-ray diffraction | A, D, G, J, M, P, S, V, Y | ZN | 20 (best 0.87) |
| 7C07 | Crystal structure of yeast U2AF1 complex bound to 5'-AAGGU RNA. | x-ray diffraction | A, D, G, J, M, P, S, V, Y | ZN | 20 (best 0.87) |
| 7C07 | Crystal structure of yeast U2AF1 complex bound to 5'-aaggu RNA. | x-ray diffraction | A, D, G, J, M, P, S, V, Y | ZN | 20 (best 0.87) |
| 7C08 | Crystal structure of S34Y mutant of yeast U2AF1 complex bound to 3' splice site RNA, 5'-UAGGU. | x-ray diffraction | A, D, G, J, M, P, S, V, Y | ZN | 20 (best 0.87) |
| 7C08 | Crystal structure of S34Y mutant of yeast U2AF1 complex bound to 3' splice site RNA, 5'-uaggu. | x-ray diffraction | A, D, G, J, M, P, S, V, Y | ZN | 20 (best 0.87) |
| Q09176 | AlphaFold monomer V2.0 prediction for splicing factor U2AF 23 kda subunit (Q09176) | predicted | A | — | 2 (best 0.31) |
Ligands
- ZN · Zinc ion · in 8 records
Experiment against prediction
- 4YH8 chain A against the predicted model Q09176: TM-score 0.98, RMSD 0.71 Å
- 4YH8 chain A against the predicted model Q09176: TM-score 0.98, RMSD 0.71 Å
- 7C06 chain M against the predicted model Q09176: TM-score 0.98, RMSD 0.81 Å
- 7C06 chain M against the predicted model Q09176: TM-score 0.98, RMSD 0.81 Å
- 7C08 chain Y against the predicted model Q09176: TM-score 0.98, RMSD 0.81 Å
- 7C08 chain Y against the predicted model Q09176: TM-score 0.98, RMSD 0.81 Å
- 7C08 chain M against the predicted model Q09176: TM-score 0.98, RMSD 0.84 Å
- 7C08 chain M against the predicted model Q09176: TM-score 0.98, RMSD 0.84 Å
- 7C07 chain M against the predicted model Q09176: TM-score 0.98, RMSD 0.84 Å
- 7C07 chain M against the predicted model Q09176: TM-score 0.98, RMSD 0.84 Å
Elsewhere
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