UniProt Q08AF3
Schlafen family member 5 (Q08AF3)
Schlafen family member 5 (UniProt Q08AF3): 8 experimental structures and 1 predicted model on GenesisL1, 3 ligands bound, 65 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q08AF3
- Protein
- Schlafen family member 5
- Experimental structures
- 8
- Predicted models
- 1
- Ligands
- 3
- Pockets
- 65 · 7 records with a druggable one
Structures
9 records of Q08AF3 in the MolNFT archive: 8 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 6RR9 | DNA/RNA binding protein | x-ray diffraction | A | ZN, SO4 | 1 (best 0.34) |
| 6RR9 | DNA/RNA binding protein | x-ray diffraction | A | ZN, SO4 | 1 (best 0.34) |
| 7CUX | Crystal structure of human Schlafen 5 N'-terminal domain (SLFN5-N) involved in ssRNA cleaving and… | x-ray diffraction | A, B, C, D, E, F | ZN | 15 (best 0.87) |
| 7CUX | Crystal structure of human schlafen 5 N'-terminal domain (SLFN5-N) involved in ssrna cleaving and… | x-ray diffraction | A, B, C, D, E, F | ZN | 15 (best 0.87) |
| 7PPJ | human SLFN5 | electron microscopy | A | ZN | 8 (best 0.63) |
| 7PPJ | HUMAN SLFN5 | electron microscopy | A | ZN | 8 (best 0.63) |
| 7Q3Z | DNA/RNA binding protein | x-ray diffraction | B, A | ZN, NA | 4 (best 0.65) |
| 7Q3Z | DNA/RNA binding protein | x-ray diffraction | B, A | ZN, NA | 4 (best 0.65) |
| Q08AF3 | AlphaFold monomer V2.0 prediction for schlafen family member 5 (Q08AF3) | predicted | A | — | 9 (best 0.80) |
Ligands
Experiment against prediction
- 7PPJ chain A against the predicted model Q08AF3: TM-score 0.98, RMSD 1.18 Å
- 7PPJ chain A against the predicted model Q08AF3: TM-score 0.98, RMSD 1.18 Å
- 7CUX chain C against the predicted model Q08AF3: TM-score 0.98, RMSD 0.87 Å
- 7CUX chain C against the predicted model Q08AF3: TM-score 0.98, RMSD 0.87 Å
- 7CUX chain A against the predicted model Q08AF3: TM-score 0.98, RMSD 0.93 Å
- 7CUX chain A against the predicted model Q08AF3: TM-score 0.98, RMSD 0.93 Å
- 7CUX chain B against the predicted model Q08AF3: TM-score 0.98, RMSD 0.97 Å
- 7CUX chain B against the predicted model Q08AF3: TM-score 0.98, RMSD 0.97 Å
- 7CUX chain F against the predicted model Q08AF3: TM-score 0.98, RMSD 0.98 Å
- 7CUX chain F against the predicted model Q08AF3: TM-score 0.98, RMSD 0.98 Å
Elsewhere
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