UniProt Q08949
DNA damage checkpoint protein 1 (Q08949)
DNA damage checkpoint protein 1 (UniProt Q08949): 4 experimental structures and 1 predicted model on GenesisL1, 5 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q08949
- Protein
- DNA damage checkpoint protein 1
- Experimental structures
- 4
- Predicted models
- 1
- Pockets
- 5 · 1 record with a druggable one
Structures
5 records of Q08949 in the MolNFT archive: 4 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 7SH2 | Structure of the yeast RAD24-rfc loader bound to DNA and the open 9-1- 1 clamp | electron microscopy | H | — | — |
| 7ST9 | Open state of RAD24-RFC:9-1-1 bound to a 5' SS/DSDNA junction | electron microscopy | G | — | — |
| 7STB | Closed state of Rad24-RFC:9-1-1 bound to a 5' ss/dsDNA junction | electron microscopy | G | — | 5 (best 0.78) |
| 7STB | Closed state of RAD24-RFC:9-1-1 bound to a 5' SS/DSDNA junction | electron microscopy | G | — | — |
| Q08949 | AlphaFold monomer V2.0 prediction for DNA damage checkpoint protein 1 (Q08949) | predicted | A | — | — |
Experiment against prediction
- 7ST9 chain G against the predicted model Q08949: TM-score 0.99, RMSD 0.82 Å
- 7STB chain G against the predicted model Q08949: TM-score 0.98, RMSD 1.00 Å
- 7STB chain G against the predicted model Q08949: TM-score 0.98, RMSD 1.00 Å
- 7SH2 chain H against the predicted model Q08949: TM-score 0.94, RMSD 1.39 Å
Elsewhere
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