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UniProt Q08467

Casein kinase II subunit alpha-1 (Q08467)

Casein kinase II subunit alpha-1 (UniProt Q08467), EC 2.7.11.1: 10 experimental structures and 1 predicted model on GenesisL1, 6 ligands bound, 9 pockets. Binding sites, druggability and experiment against prediction (TM-score)…

UniProt
Q08467
Protein
Casein kinase II subunit alpha-1
EC
2.7.11.1
Experimental structures
10
Predicted models
1
Ligands
6
Pockets
9 · 5 records with a druggable one

Structures

11 records of Q08467 in the MolNFT archive: 10 experimental, 1 predicted.

EntryTitleMethodChainsLigandsPockets
6XX6Arabidopsis thaliana Casein Kinase 2 (CK2) alpha-1 crystal form Ix-ray diffractionAPIV, SO4, CL2 (best 0.65)
6XX6Arabidopsis thaliana casein kinase 2 (CK2) alpha-1 crystal form Ix-ray diffractionAPIV, SO4, CL—
6XX7Arabidopsis thaliana Casein Kinase 2 (CK2) alpha-1 crystal in complex with ANPx-ray diffractionAANP, MG, SO4, CL1 (best 0.66)
6XX7Arabidopsis thaliana casein kinase 2 (CK2) alpha-1 crystal in complex with anpx-ray diffractionAANP, MG, SO4, CL—
6XX8Arabidopsis thaliana Casein Kinase 2 (CK2) alpha-1 crystal form IIx-ray diffractionA, B—3 (best 0.83)
6XX8Arabidopsis thaliana casein kinase 2 (CK2) alpha-1 crystal form IIx-ray diffractionA, B——
6XX9Arabidopsis thaliana Casein Kinase 2 (CK2) alpha-1 crystal form IIIx-ray diffractionASO41 (best 0.68)
6XX9Arabidopsis thaliana casein kinase 2 (CK2) alpha-1 crystal form IIIx-ray diffractionASO4—
6Z1CCrystal structure of Arabidopsis thaliana CK2-alpha-1 in complex with TTP-22x-ray diffractionA7EY, CL2 (best 0.66)
6Z1CCrystal structure of arabidopsis thaliana CK2-alpha-1 in complex with ttp-22x-ray diffractionA7EY, CL—
Q08467AlphaFold monomer V2.0 prediction for casein kinase II subunit alpha-1 (Q08467)predictedA——

Ligands

  • CL · Chloride ion · in 6 records
  • SO4 · Sulfate ion · in 6 records
  • 7EY · 3-[5-(4-methylphenyl)thieno[2,3-d]pyrimidin-4-yl]sulfanylpropanoic acid · in 2 records
  • ANP · Phosphoaminophosphonic acid-adenylate ester · in 2 records
  • MG · Magnesium ion · in 2 records
  • PIV · Pivalic acid · in 2 records

Experiment against prediction

Elsewhere

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