UniProt Q08032
Cell division control protein 45 (Q08032)
Cell division control protein 45 (UniProt Q08032): 22 experimental structures and 1 predicted model on GenesisL1, 27 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q08032
- Protein
- Cell division control protein 45
- Experimental structures
- 22
- Predicted models
- 1
- Pockets
- 27 · 8 records with a druggable one
Structures
23 records of Q08032 in the MolNFT archive: 22 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 3JC5 | Structure of the eukaryotic replicative CMG helicase and pumpjack motion | electron microscopy | c | — | — |
| 3JC5 | Structure of the eukaryotic replicative cmg helicase and pumpjack motion | electron microscopy | c | — | — |
| 3JC6 | Structure of the eukaryotic replicative CMG helicase and pumpjack motion | electron microscopy | E | — | — |
| 3JC6 | Structure of the eukaryotic replicative cmg helicase and pumpjack motion | electron microscopy | E | — | — |
| 3JC7 | Structure of the eukaryotic replicative CMG helicase and pumpjack motion | electron microscopy | c | — | — |
| 3JC7 | Structure of the eukaryotic replicative cmg helicase and pumpjack motion | electron microscopy | c | — | — |
| 5U8S | Structure of eukaryotic CMG helicase at a replication fork | electron microscopy | E | — | 4 (best 0.87) |
| 5U8S | Structure of eukaryotic cmg helicase at a replication fork | electron microscopy | E | — | — |
| 5U8T | Structure of Eukaryotic CMG Helicase at a Replication Fork and Implications | electron microscopy | E | — | 3 (best 0.87) |
| 5U8T | Structure of eukaryotic cmg helicase at a replication fork and implications | electron microscopy | E | — | — |
| 6HV9 | S. cerevisiae cmg-pol epsilon-DNA | electron microscopy | G | — | — |
| 6PTJ | Structure of Ctf4 trimer in complex with one CMG helicase | electron microscopy | c | — | — |
| 6PTJ | Structure of CTF4 trimer in complex with one cmg helicase | electron microscopy | c | — | — |
| 6PTN | Structure of CTF4 trimer in complex with two cmg helicases | electron microscopy | h, H | — | — |
| 6SKL | Cryo-EM structure of the CMG Fork Protection Complex at a replication fork - Conformation 1 | electron microscopy | E | — | 2 (best 0.85) |
| 6U0M | Structure of the S. cerevisiae replicative helicase CMG in complex with a forked DNA | electron microscopy | E | — | 4 (best 0.89) |
| 6U0M | Structure of the S. cerevisiae replicative helicase cmg in complex with a forked DNA | electron microscopy | E | — | — |
| 7QHS | S. cerevisiae CMGE nucleating origin DNA melting | electron microscopy | E | — | 4 (best 0.87) |
| 7Z13 | S. cerevisiae CMGE dimer nucleating origin DNA melting | electron microscopy | E, L | — | 5 (best 0.87) |
| 8B9B | S. cerevisiae replisome + Ctf4, bound by pol alpha. Complex engaged with a fork DNA substrate… | electron microscopy | G | — | — |
| 8P63 | S. cerevisiae consensus-sCMGE on ssDNA after DNA replication initiation | electron microscopy | E | — | 3 (best 0.88) |
| 8W7M | Yeast replisome in state V | electron microscopy | E | — | 2 (best 0.85) |
| Q08032 | AlphaFold monomer V2.0 prediction for cell division control protein 45 (Q08032) | predicted | A | — | — |
Experiment against prediction
- 6SKL chain E against the predicted model Q08032: TM-score 0.99, RMSD 1.07 Å
- 8W7M chain E against the predicted model Q08032: TM-score 0.98, RMSD 1.13 Å
- 8B9B chain G against the predicted model Q08032: TM-score 0.98, RMSD 1.22 Å
- 8P63 chain E against the predicted model Q08032: TM-score 0.98, RMSD 1.29 Å
- 7Z13 chain L against the predicted model Q08032: TM-score 0.98, RMSD 1.33 Å
- 7Z13 chain E against the predicted model Q08032: TM-score 0.98, RMSD 1.33 Å
- 7QHS chain E against the predicted model Q08032: TM-score 0.98, RMSD 1.33 Å
- 5U8T chain E against the predicted model Q08032: TM-score 0.98, RMSD 1.36 Å
- 5U8T chain E against the predicted model Q08032: TM-score 0.98, RMSD 1.36 Å
- 3JC6 chain E against the predicted model Q08032: TM-score 0.97, RMSD 1.42 Å
Elsewhere
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