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UniProt Q07008

Neurogenic locus notch homolog protein 1 (Q07008)

Neurogenic locus notch homolog protein 1 (UniProt Q07008): 9 experimental structures on GenesisL1, 5 ligands bound, 10 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.

UniProt
Q07008
Protein
Neurogenic locus notch homolog protein 1
Experimental structures
9
Predicted models
0
Ligands
5
Pockets
10 · 2 records with a druggable one

Structures

9 records of Q07008 in the MolNFT archive: 9 experimental, 0 predicted.

EntryTitleMethodChainsLigandsPockets
1YMPThe Crystal Structure of a Partial Mouse Notch-1 Ankyrin Domain: Repeats 4 Through 7 Preserve an…x-ray diffractionA, B——
1YMPThe crystal structure of a partial mouse notch-1 ankyrin domain: repeats 4 through 7 preserve an…x-ray diffractionA, B——
4XL1Complex of Notch1 (EGF11-13) bound to Delta-like 4 (N-EGF1)x-ray diffractionA, D——
4XL1Complex of NOTCH1 (EGF11-13) bound to delta-like 4 (N-EGF1)x-ray diffractionA, D——
4XLWComplex of Notch1 (EGF11-13) bound to Delta-like 4 (N-EGF2)x-ray diffractionA, C, E, GCA, BGC, FUC, NAG8 (best 0.63)
4XLWComplex of NOTCH1 (EGF11-13) bound to delta-like 4 (N-EGF2)x-ray diffractionA, C, E, G——
5UK5Complex of Notch1(EGF8-12) bound to Jagged1(N-EGF3)x-ray diffractionABGC, XYS, CA, FUC, NAG2 (best 0.60)
5UK5Complex of NOTCH1(EGF8-12) bound to JAGGED1(N-EGF3)x-ray diffractionABGC, XYS, CA, FUC, NAG—
Q07008AlphaFold monomer V2.0 prediction for neurogenic locus notch homolog protein 1 (Q07008)———

Ligands

  • BGC · beta-D-glucopyranose · in 3 records
  • CA · Calcium ion · in 3 records
  • FUC · alpha-L-fucopyranose · in 3 records
  • NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose · in 3 records
  • XYS · alpha-D-xylopyranose · in 2 records

Elsewhere

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