UniProt Q06481
Amyloid-like protein 2 (Q06481)
Amyloid-like protein 2 (UniProt Q06481): 5 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 5 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q06481
- Protein
- Amyloid-like protein 2
- Experimental structures
- 5
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 5 · 2 records with a druggable one
Structures
6 records of Q06481 in the MolNFT archive: 5 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 5JBT | Mesotrypsin in complex with cleaved amyloid precursor like protein 2 inhibitor (APLP2) | x-ray diffraction | X, Y | SO4 | 1 (best 0.57) |
| 5JBT | Mesotrypsin in complex with cleaved amyloid precursor like protein 2 inhibitor (APLP2) | x-ray diffraction | X, Y | — | — |
| 5TPT | The Crystal Structure of Amyloid Precursor-Like Protein 2 (APLP2) E2 Domain | x-ray diffraction | A, B | — | 4 (best 0.73) |
| 5TPT | The crystal structure of amyloid precursor-like protein 2 (APLP2) E2 domain | x-ray diffraction | A, B | — | — |
| 8RQ6 | Solution NMR structure of Amyloid beta precursor like protein 2 TMD | solution nmr | A | — | — |
| Q06481 | AlphaFold monomer V2.0 prediction for amyloid-like protein 2 (Q06481) | predicted | A | — | — |
Ligands
- SO4 · Sulfate ion · in 1 record
Experiment against prediction
- 5TPT chain B against the predicted model Q06481: TM-score 0.94, RMSD 1.35 Å
- 5TPT chain B against the predicted model Q06481: TM-score 0.94, RMSD 1.35 Å
- 5TPT chain A against the predicted model Q06481: TM-score 0.91, RMSD 1.71 Å
- 5TPT chain A against the predicted model Q06481: TM-score 0.91, RMSD 1.71 Å
- 8RQ6 chain A against the predicted model Q06481: TM-score 0.54, RMSD 1.55 Å
- 5JBT chain Y against the predicted model Q06481: TM-score 0.43, RMSD 3.32 Å
- 5JBT chain Y against the predicted model Q06481: TM-score 0.43, RMSD 3.32 Å
- 5JBT chain X against the predicted model Q06481: TM-score 0.28, RMSD 2.65 Å
- 5JBT chain X against the predicted model Q06481: TM-score 0.28, RMSD 2.65 Å
Elsewhere
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