UniProt Q06323
Proteasome activator complex subunit 1 (Q06323)
Proteasome activator complex subunit 1 (UniProt Q06323): 7 experimental structures and 1 predicted model on GenesisL1, 29 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q06323
- Protein
- Proteasome activator complex subunit 1
- Experimental structures
- 7
- Predicted models
- 1
- Pockets
- 29 · 3 records with a druggable one
Structures
8 records of Q06323 in the MolNFT archive: 7 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1AVO | Proteasome activator REG(ALPHA) | x-ray diffraction | A, B, C, D, E, F, G, H, I, J, K, L, M, N | — | — |
| 1AVO | Proteasome activator REG(ALPHA) | x-ray diffraction | A, B, C, D, E, F, G, H, I, J, K, L, M, N | — | — |
| 7DR6 | PA28ALPHA-beta in complex with immunoproteasome | electron microscopy | B, C, E, G | — | — |
| 7DRW | Bovine 20S immunoproteasome in complex with two human PA28alpha-beta activators | electron microscopy | I, J, L, N, Q, a, e, i | — | 11 (best 0.86) |
| 7DRW | Bovine 20S immunoproteasome in complex with two human PA28ALPHA-beta activators | electron microscopy | I, J, L, N, Q, a, e, i | — | — |
| 7NAP | Human PA28-20S-PA28 proteasome complex | electron microscopy | j, l, n, c, e, g | — | 13 (best 0.83) |
| 8CXB | Human PA28-20S (PA28-4a3b) | electron microscopy | d, f, h, i | — | 5 (best 0.79) |
| Q06323 | AlphaFold monomer V2.0 prediction for proteasome activator complex subunit 1 (Q06323) | predicted | A | — | — |
Experiment against prediction
- 1AVO chain B against the predicted model Q06323: TM-score 0.98, RMSD 0.55 Å
- 1AVO chain B against the predicted model Q06323: TM-score 0.98, RMSD 0.55 Å
- 7NAP chain j against the predicted model Q06323: TM-score 0.97, RMSD 1.27 Å
- 7NAP chain c against the predicted model Q06323: TM-score 0.97, RMSD 1.27 Å
- 8CXB chain f against the predicted model Q06323: TM-score 0.97, RMSD 0.89 Å
- 7NAP chain g against the predicted model Q06323: TM-score 0.97, RMSD 1.31 Å
- 7NAP chain n against the predicted model Q06323: TM-score 0.97, RMSD 1.31 Å
- 7NAP chain e against the predicted model Q06323: TM-score 0.97, RMSD 1.25 Å
- 7NAP chain l against the predicted model Q06323: TM-score 0.97, RMSD 1.25 Å
- 8CXB chain i against the predicted model Q06323: TM-score 0.96, RMSD 1.47 Å
Elsewhere
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