UniProt Q06151
m7GpppX diphosphatase (Q06151)
m7GpppX diphosphatase (UniProt Q06151), EC 3.6.1.59: 4 experimental structures and 1 predicted model on GenesisL1, 6 ligands bound, 37 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q06151
- Protein
- m7GpppX diphosphatase
- EC
- 3.6.1.59
- Experimental structures
- 4
- Predicted models
- 1
- Ligands
- 6
- Pockets
- 37 · 2 records with a druggable one
Structures
5 records of Q06151 in the MolNFT archive: 4 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 5BV3 | Yeast Scavenger Decapping Enzyme in complex with m7GDP | x-ray diffraction | A, B, C, D | M7G, SO4, CL | 17 (best 0.87) |
| 5BV3 | Yeast scavenger decapping enzyme in complex with M7GDP | x-ray diffraction | A, B, C, D | — | — |
| 6TRQ | S.c. Scavenger Decapping Enzyme DcpS in complex with the capped RNA dinucleotide m7G-GU | x-ray diffraction | A, B, C, D | 2PO, U, 0G, M7G, SO4 | 20 (best 0.86) |
| 6TRQ | S.C. scavenger decapping enzyme dcps in complex with the capped RNA dinucleotide M7G-gu | x-ray diffraction | A, B, C, D | 2PO, U, 0G, M7G, SO4 | — |
| Q06151 | AlphaFold monomer V2.0 prediction for M7GPPPX diphosphatase (Q06151) | predicted | A | — | — |
Ligands
Experiment against prediction
- 5BV3 chain A against the predicted model Q06151: TM-score 1.00, RMSD 0.40 Å
- 5BV3 chain A against the predicted model Q06151: TM-score 1.00, RMSD 0.40 Å
- 6TRQ chain A against the predicted model Q06151: TM-score 0.99, RMSD 0.55 Å
- 6TRQ chain A against the predicted model Q06151: TM-score 0.99, RMSD 0.55 Å
- 5BV3 chain C against the predicted model Q06151: TM-score 0.99, RMSD 0.61 Å
- 5BV3 chain C against the predicted model Q06151: TM-score 0.99, RMSD 0.61 Å
- 6TRQ chain C against the predicted model Q06151: TM-score 0.99, RMSD 0.68 Å
- 6TRQ chain C against the predicted model Q06151: TM-score 0.99, RMSD 0.68 Å
- 5BV3 chain D against the predicted model Q06151: TM-score 0.70, RMSD 3.81 Å
- 5BV3 chain D against the predicted model Q06151: TM-score 0.70, RMSD 3.81 Å
Elsewhere
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.