UniProt Q06078
U3 small nucleolar RNA-associated protein 21 (Q06078)
U3 small nucleolar RNA-associated protein 21 (UniProt Q06078): 32 experimental structures and 1 predicted model on GenesisL1, 54 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q06078
- Protein
- U3 small nucleolar RNA-associated protein 21
- Experimental structures
- 32
- Predicted models
- 1
- Pockets
- 54 · 17 records with a druggable one
Structures
33 records of Q06078 in the MolNFT archive: 32 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 4NSX | Crystal Structure of the Utp21 tandem WD Domain | x-ray diffraction | A | — | — |
| 4NSX | Crystal structure of the UTP21 tandem wd domain | x-ray diffraction | A | — | — |
| 5JPQ | Cryo-EM structure of the 90S pre-ribosome | electron microscopy | I | — | 2 (best 0.83) |
| 5JPQ | Cryo-EM structure of the 90S pre-ribosome | electron microscopy | I | — | — |
| 5TZS | Architecture of the yeast small subunit processome | electron microscopy | T | — | 2 (best 0.80) |
| 5TZS | Architecture of the yeast small subunit processome | electron microscopy | T | — | — |
| 5WLC | The complete structure of the small subunit processome | electron microscopy | LT | — | — |
| 5WYJ | Cryo-EM structure of the 90S small subunit pre-ribosome (Dhr1-depleted, Enp1-TAP, state 1) | electron microscopy | BE | — | 3 (best 0.85) |
| 5WYK | Cryo-EM structure of the 90S small subunit pre-ribosome (Mtr4-depleted, Enp1-TAP) | electron microscopy | BE | — | — |
| 6KE6 | 3.4 angstrom cryo-EM structure of yeast 90S small subunit preribosome | electron microscopy | BE | — | 2 (best 0.88) |
| 6LQP | Cryo-EM structure of 90S small subunit preribosomes in transition states (State A) | electron microscopy | BE | — | — |
| 6LQQ | Cryo-EM structure of 90S small subunit preribosomes in transition states (State B) | electron microscopy | BE | — | — |
| 6LQR | Cryo-EM structure of 90S small subunit preribosomes in transition states (State C) | electron microscopy | BE | — | — |
| 6LQS | Cryo-EM structure of 90S small subunit preribosomes in transition states (State D) | electron microscopy | BE | — | — |
| 6LQT | Cryo-EM structure of 90S small subunit preribosomes in transition states (State E) | electron microscopy | BE | — | — |
| 6LQU | Cryo-EM structure of 90S small subunit preribosomes in transition states (State A1) | electron microscopy | BE | — | — |
| 6LQV | Cryo-EM structure of 90S small subunit preribosomes in transition states (State C1) | electron microscopy | BE | — | — |
| 6ND4 | Conformational switches control early maturation of the eukaryotic small ribosomal subunit | electron microscopy | T | — | — |
| 6ND4 | Conformational switches control early maturation of the eukaryotic small ribosomal subunit | electron microscopy | T | — | — |
| 6ZQA | Cryo-EM structure of the 90S pre-ribosome from Saccharomyces cerevisiae, state A (Poly-Ala) | electron microscopy | UU | — | 1 (best 0.82) |
| 6ZQB | Cryo-EM structure of the 90S pre-ribosome from Saccharomyces cerevisiae, state B2 | electron microscopy | UU | — | 4 (best 0.88) |
| 6ZQC | Cryo-EM structure of the 90S pre-ribosome from Saccharomyces cerevisiae, state Pre-A1 | electron microscopy | UU | — | 2 (best 0.88) |
| 6ZQD | Cryo-EM structure of the 90S pre-ribosome from Saccharomyces cerevisiae, state Post-A1 | electron microscopy | UU | — | 3 (best 0.87) |
| 6ZQE | Cryo-EM structure of the 90S pre-ribosome from Saccharomyces cerevisiae, state Dis-A (Poly-Ala) | electron microscopy | UU | — | — |
| 6ZQF | Cryo-EM structure of the 90S pre-ribosome from Saccharomyces cerevisiae, state Dis-B (Poly-Ala) | electron microscopy | UU | — | 1 (best 0.80) |
| 7AJT | Cryo-EM structure of the 90S-exosome super-complex (state Pre-A1-exosome) | electron microscopy | UU | — | 3 (best 0.88) |
| 7AJU | Cryo-EM structure of the 90S-exosome super-complex (state Post-A1-exosome) | electron microscopy | UU | — | 5 (best 0.87) |
| 7D4I | Cryo-EM structure of 90S small ribosomal precursors complex with the DEAH-box RNA helicase Dhr1… | electron microscopy | BE | — | 3 (best 0.86) |
| 7D5S | Cryo-EM structure of 90S preribosome with inactive Utp24 (state A2) | electron microscopy | BE | — | 3 (best 0.87) |
| 7D5T | Cryo-EM structure of 90S preribosome with inactive Utp24 (state F1) | electron microscopy | BE | — | 3 (best 0.85) |
| 7D63 | Cryo-EM structure of 90S preribosome with inactive Utp24 (state C) | electron microscopy | BE | — | 4 (best 0.87) |
| 7SUK | Structure of Bfr2-Lcp5 Complex Observed in the Small Subunit Processome Isolated from R2TP-depleted… | electron microscopy | LT | — | 4 (best 0.87) |
| Q06078 | AlphaFold monomer V2.0 prediction for U3 small nucleolar RNA- associated protein 21 (Q06078) | predicted | A | — | 9 (best 0.77) |
Experiment against prediction
- 5JPQ chain I against the predicted model Q06078: TM-score 0.99, RMSD 1.08 Å
- 5JPQ chain I against the predicted model Q06078: TM-score 0.99, RMSD 1.08 Å
- 4NSX chain A against the predicted model Q06078: TM-score 0.99, RMSD 1.08 Å
- 4NSX chain A against the predicted model Q06078: TM-score 0.99, RMSD 1.08 Å
- 5WYJ chain BE against the predicted model Q06078: TM-score 0.95, RMSD 2.44 Å
- 5WYK chain BE against the predicted model Q06078: TM-score 0.93, RMSD 2.67 Å
- 5TZS chain T against the predicted model Q06078: TM-score 0.92, RMSD 2.85 Å
- 5TZS chain T against the predicted model Q06078: TM-score 0.92, RMSD 2.85 Å
- 7D63 chain BE against the predicted model Q06078: TM-score 0.92, RMSD 3.20 Å
- 6LQR chain BE against the predicted model Q06078: TM-score 0.92, RMSD 3.20 Å
Elsewhere
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