UniProt Q05776
Protein UPS1, mitochondrial (Q05776)
Protein UPS1, mitochondrial (UniProt Q05776): 14 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 36 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q05776
- Protein
- Protein UPS1, mitochondrial
- Experimental structures
- 14
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 36 · 4 records with a druggable one
Structures
15 records of Q05776 in the MolNFT archive: 14 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 4XHR | Structure of a phospholipid trafficking complex, native | x-ray diffraction | A, B | — | — |
| 4XHR | Structure of a phospholipid trafficking complex, native | x-ray diffraction | A, B | — | — |
| 4XIZ | Structure of a phospholipid trafficking complex with substrate | x-ray diffraction | A, B | — | — |
| 4XIZ | Structure of a phospholipid trafficking complex with substrate | x-ray diffraction | A, B | — | — |
| 4YTW | Crystal structure of Ups1-Mdm35 complex | x-ray diffraction | B, D | — | — |
| 4YTW | Crystal structure of UPS1-MDM35 complex | x-ray diffraction | B, D | — | — |
| 4YTX | Crystal structure of Ups1-Mdm35 complex with PA | x-ray diffraction | B, D, F, H, J, L, N, P | — | — |
| 4YTX | Crystal structure of UPS1-MDM35 complex with pa | x-ray diffraction | B, D, F, H, J, L, N, P | — | — |
| 5JQL | Crystal Structure of Phosphatidic acid Transporter Ups1/Mdm35 Void of Bound Phospholipid from… | x-ray diffraction | A, C, E, G, I, K | — | 20 (best 0.87) |
| 5JQL | Crystal structure of phosphatidic acid transporter UPS1/MDM35 void of bound phospholipid from… | x-ray diffraction | A, C, E, G, I, K | — | — |
| 5JQM | Crystal Structure of Phosphatidic acid Transporter Ups1/Mdm35 Void of Bound Phospholipid from… | x-ray diffraction | A, B, C | — | 7 (best 0.90) |
| 5JQM | Crystal structure of phosphatidic acid transporter UPS1/MDM35 void of bound phospholipid from… | x-ray diffraction | A, B, C | — | — |
| 6KYL | Crystal Structure of Phosphatidic acid Transporter Ups1/Mdm35 in Complex with… | x-ray diffraction | B, D | 44E | 8 (best 0.77) |
| 6KYL | Crystal structure of phosphatidic acid transporter UPS1/MDM35 in complex with… | x-ray diffraction | B, D | 44E | — |
| Q05776 | AlphaFold monomer V2.0 prediction for protein UPS1, mitochondrial (Q05776) | predicted | A | — | 1 (best 0.84) |
Ligands
- 44E · (2R)-3-(phosphonooxy)propane-1,2-diyl dihexanoate · in 2 records
Experiment against prediction
- 4XHR chain A against the predicted model Q05776: TM-score 0.97, RMSD 1.00 Å
- 4XHR chain A against the predicted model Q05776: TM-score 0.97, RMSD 1.00 Å
- 4XIZ chain A against the predicted model Q05776: TM-score 0.97, RMSD 1.15 Å
- 4XIZ chain A against the predicted model Q05776: TM-score 0.97, RMSD 1.15 Å
- 5JQM chain A against the predicted model Q05776: TM-score 0.70, RMSD 1.03 Å
- 5JQM chain A against the predicted model Q05776: TM-score 0.70, RMSD 1.03 Å
- 5JQM chain B against the predicted model Q05776: TM-score 0.70, RMSD 1.12 Å
- 5JQM chain B against the predicted model Q05776: TM-score 0.70, RMSD 1.12 Å
- 5JQM chain C against the predicted model Q05776: TM-score 0.68, RMSD 1.06 Å
- 5JQM chain C against the predicted model Q05776: TM-score 0.68, RMSD 1.06 Å
Elsewhere
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