UniProt Q05096
Unconventional myosin-Ib (Q05096)
Unconventional myosin-Ib (UniProt Q05096): 10 experimental structures and 1 predicted model on GenesisL1, 3 ligands bound, 67 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q05096
- Protein
- Unconventional myosin-Ib
- Experimental structures
- 10
- Predicted models
- 1
- Ligands
- 3
- Pockets
- 67 · 7 records with a druggable one
Structures
11 records of Q05096 in the MolNFT archive: 10 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 4L79 | Crystal Structure of nucleotide-free Myosin 1b residues 1-728 with bound Calmodulin | x-ray diffraction | A | MG | 11 (best 0.69) |
| 4L79 | Crystal structure of nucleotide-free myosin 1B residues 1-728 with bound calmodulin | x-ray diffraction | A | MG | 11 (best 0.69) |
| 5V7X | Crystal Structure of Myosin 1b residues 1-728 with bound sulfate and Calmodulin | x-ray diffraction | A | SO4 | 12 (best 0.74) |
| 5V7X | Crystal structure of myosin 1B residues 1-728 with bound sulfate and calmodulin | x-ray diffraction | A | SO4 | — |
| 6C1D | High-Resolution Cryo-EM Structures of Actin-bound Myosin States Reveal the Mechanism of Myosin… | electron microscopy | P | MG, ADP | 8 (best 0.77) |
| 6C1D | High-resolution cryo-EM structures of actin-bound myosin states reveal the mechanism of myosin… | electron microscopy | P | MG, ADP | — |
| 6C1G | High-Resolution Cryo-EM Structures of Actin-bound Myosin States Reveal the Mechanism of Myosin… | electron microscopy | P | MG, ADP | 7 (best 0.79) |
| 6C1G | High-resolution cryo-EM structures of actin-bound myosin states reveal the mechanism of myosin… | electron microscopy | P | MG, ADP | — |
| 6C1H | High-Resolution Cryo-EM Structures of Actin-bound Myosin States Reveal the Mechanism of Myosin… | electron microscopy | P | — | 7 (best 0.78) |
| 6C1H | High-resolution cryo-EM structures of actin-bound myosin states reveal the mechanism of myosin… | electron microscopy | P | — | — |
| Q05096 | AlphaFold monomer V2.0 prediction for unconventional myosin-ib (Q05096) | predicted | A | — | 11 (best 0.69) |
Ligands
Experiment against prediction
- 5V7X chain A against the predicted model Q05096: TM-score 0.99, RMSD 1.13 Å
- 5V7X chain A against the predicted model Q05096: TM-score 0.99, RMSD 1.13 Å
- 6C1H chain P against the predicted model Q05096: TM-score 0.98, RMSD 1.29 Å
- 6C1H chain P against the predicted model Q05096: TM-score 0.98, RMSD 1.29 Å
- 6C1G chain P against the predicted model Q05096: TM-score 0.98, RMSD 1.50 Å
- 6C1G chain P against the predicted model Q05096: TM-score 0.98, RMSD 1.50 Å
- 4L79 chain A against the predicted model Q05096: TM-score 0.97, RMSD 1.88 Å
- 4L79 chain A against the predicted model Q05096: TM-score 0.97, RMSD 1.88 Å
- 6C1D chain P against the predicted model Q05096: TM-score 0.89, RMSD 3.25 Å
- 6C1D chain P against the predicted model Q05096: TM-score 0.89, RMSD 3.25 Å
Elsewhere
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