UniProt Q04437
ATP-dependent DNA helicase II subunit 2 (Q04437)
ATP-dependent DNA helicase II subunit 2 (UniProt Q04437), EC 3.6.4.12: 4 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 20 pockets. Binding sites, druggability and experiment against prediction…
- UniProt
- Q04437
- Protein
- ATP-dependent DNA helicase II subunit 2
- EC
- 3.6.4.12
- Experimental structures
- 4
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 20 · 1 record with a druggable one
Structures
5 records of Q04437 in the MolNFT archive: 4 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 5Y58 | Crystal structure of Ku70/80 and TLC1 | x-ray diffraction | B, D, F | — | 20 (best 0.85) |
| 5Y58 | Crystal structure of KU70/80 and TLC1 | x-ray diffraction | B, D, F | — | — |
| 5Y59 | Crystal structure of Ku80 and Sir4 | x-ray diffraction | B | SO4 | — |
| 5Y59 | Crystal structure of KU80 and SIR4 | x-ray diffraction | B | SO4 | — |
| Q04437 | AlphaFold monomer V2.0 prediction for ATP-dependent DNA helicase II subunit 2 (Q04437) | predicted | A | — | — |
Ligands
- SO4 · Sulfate ion · in 2 records
Experiment against prediction
- 5Y59 chain B against the predicted model Q04437: TM-score 0.94, RMSD 1.51 Å
- 5Y59 chain B against the predicted model Q04437: TM-score 0.94, RMSD 1.51 Å
- 5Y58 chain F against the predicted model Q04437: TM-score 0.93, RMSD 2.25 Å
- 5Y58 chain F against the predicted model Q04437: TM-score 0.93, RMSD 2.25 Å
- 5Y58 chain D against the predicted model Q04437: TM-score 0.93, RMSD 2.18 Å
- 5Y58 chain D against the predicted model Q04437: TM-score 0.93, RMSD 2.18 Å
- 5Y58 chain B against the predicted model Q04437: TM-score 0.93, RMSD 2.31 Å
- 5Y58 chain B against the predicted model Q04437: TM-score 0.93, RMSD 2.31 Å
Elsewhere
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