UniProt Q04377
DNA damage checkpoint protein LCD1 (Q04377)
DNA damage checkpoint protein LCD1 (UniProt Q04377): 9 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 17 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q04377
- Protein
- DNA damage checkpoint protein LCD1
- Experimental structures
- 9
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 17 · 2 records with a druggable one
Structures
10 records of Q04377 in the MolNFT archive: 9 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 5OMD | Crystal structure of S. cerevisiae Ddc2 N-terminal coiled-coil domain | x-ray diffraction | A | — | — |
| 5OMD | Crystal structure of S. cerevisiae DDC2 N-terminal coiled-coil domain | x-ray diffraction | A | — | — |
| 5X6O | Intact ATR/MEC1-ATRIP/DDC2 complex | electron microscopy | G | — | — |
| 6Z2W | Mec1-Ddc2 (F2244L mutant) in complex with Mg AMP-PNP | electron microscopy | D, C | — | 7 (best 0.87) |
| 6Z2W | MEC1-DDC2 (F2244L mutant) in complex with mg AMP-pnp | electron microscopy | D, C | — | — |
| 6Z2X | MEC1-DDC2 (F2244L mutant) in complex with mg AMP-pnp (state II) | electron microscopy | D, C | — | — |
| 6Z3A | MEC1-DDC2 (wild-type) in complex with AMP-pnp | electron microscopy | C, D | — | — |
| 7WZW | Cryo-EM structure of MEC1-DDC2-MMS | electron microscopy | C, D | — | 10 (best 0.86) |
| 8B4J | Rfa1-N-terminal domain in complex with phosphorylated Ddc2 | x-ray diffraction | P | ZN | — |
| Q04377 | AlphaFold monomer V2.0 prediction for DNA damage checkpoint protein LCD1 (Q04377) | predicted | A | — | — |
Ligands
- ZN · Zinc ion · in 1 record
Experiment against prediction
- 6Z2W chain C against the predicted model Q04377: TM-score 0.86, RMSD 2.22 Å
- 6Z2W chain D against the predicted model Q04377: TM-score 0.86, RMSD 2.21 Å
- 6Z2W chain D against the predicted model Q04377: TM-score 0.86, RMSD 2.21 Å
- 6Z2X chain D against the predicted model Q04377: TM-score 0.86, RMSD 2.22 Å
- 6Z3A chain C against the predicted model Q04377: TM-score 0.86, RMSD 2.23 Å
- 7WZW chain D against the predicted model Q04377: TM-score 0.83, RMSD 2.67 Å
- 7WZW chain C against the predicted model Q04377: TM-score 0.83, RMSD 2.80 Å
- 5OMD chain A against the predicted model Q04377: TM-score 0.79, RMSD 1.99 Å
- 5OMD chain A against the predicted model Q04377: TM-score 0.79, RMSD 1.99 Å
- 5X6O chain G against the predicted model Q04377: TM-score 0.67, RMSD 2.96 Å
Elsewhere
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