UniProt Q02939
General transcription and DNA repair factor IIH subunit TFB2 (Q02939)
General transcription and DNA repair factor IIH subunit TFB2 (UniProt Q02939): 38 experimental structures and 1 predicted model on GenesisL1, 49 pockets. Binding sites, druggability and experiment against prediction (TM-score) in…
- UniProt
- Q02939
- Protein
- General transcription and DNA repair factor IIH subunit TFB2
- Experimental structures
- 38
- Predicted models
- 1
- Pockets
- 49 · 16 records with a druggable one
Structures
39 records of Q02939 in the MolNFT archive: 38 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 3DGP | Crystal Structure of the complex between Tfb5 and the C-terminal domain of Tfb2 | x-ray diffraction | A | — | — |
| 3DGP | Crystal structure of the complex between TFB5 and the C-terminal domain of TFB2 | x-ray diffraction | A | — | — |
| 3DOM | Crystal Structure of the complex between Tfb5 and the C-terminal domain of Tfb2 | x-ray diffraction | A, C | — | — |
| 3DOM | Crystal structure of the complex between TFB5 and the C-terminal domain of TFB2 | x-ray diffraction | A, C | — | — |
| 5FMF | the P-lobe of RNA polymerase II pre-initiation complex | electron microscopy | W | — | — |
| 5FMF | The P-lobe of RNA polymerase II pre-initiation complex | electron microscopy | W | — | — |
| 5OQJ | Structure of yeast transcription pre-initiation complex with tfiih | electron microscopy | 2 | — | — |
| 5OQM | Structure of yeast transcription pre-initiation complex with tfiih and core mediator | electron microscopy | 2 | — | — |
| 5OQM | Structure of yeast transcription pre-initiation complex with tfiih and core mediator | electron microscopy | 2 | — | — |
| 5SVA | Mediator-RNA Polymerase II Pre-Initiation Complex | electron microscopy | a | — | — |
| 5SVA | Mediator-RNA polymerase II pre-initiation complex | electron microscopy | a | — | — |
| 6GYM | Structure of a yeast closed complex with distorted DNA (CCdist) | electron microscopy | 2 | — | — |
| 6GYM | Structure of a yeast closed complex with distorted DNA (ccdist) | electron microscopy | 2 | — | — |
| 7K01 | Structure of TFIIH in TFIIH/Rad4-Rad23-Rad33 DNA opening complex | electron microscopy | 2 | — | 7 (best 0.83) |
| 7K01 | Structure of tfiih in TFIIH/RAD4-RAD23-RAD33 DNA opening complex | electron microscopy | 2 | — | — |
| 7K04 | Structure of TFIIH/Rad4-Rad23-Rad33/DNA in DNA opening | electron microscopy | 2 | — | 4 (best 0.82) |
| 7K04 | Structure of TFIIH/RAD4-RAD23-RAD33/DNA in DNA opening | electron microscopy | 2 | — | — |
| 7M2U | Nucleotide Excision Repair complex TFIIH Rad4-33 | electron microscopy | 2 | — | 5 (best 0.82) |
| 7M2U | Nucleotide excision repair complex tfiih RAD4-33 | electron microscopy | 2 | — | — |
| 7O4I | Yeast RNA polymerase II transcription pre-initiation complex with initial transcription bubble | electron microscopy | 2 | — | 1 (best 0.77) |
| 7O4I | Yeast RNA polymerase II transcription pre-initiation complex with initial transcription bubble | electron microscopy | 2 | — | — |
| 7O4J | Yeast RNA polymerase II transcription pre-initiation complex (consensus) | electron microscopy | 2 | — | 2 (best 0.80) |
| 7O4J | Yeast RNA polymerase II transcription pre-initiation complex (consensus) | electron microscopy | 2 | — | — |
| 7O4K | Yeast TFIIH in the contracted state within the pre-initiation complex | electron microscopy | 2 | — | 3 (best 0.80) |
| 7O4K | Yeast tfiih in the contracted state within the pre-initiation complex | electron microscopy | 2 | — | — |
| 7O4L | Yeast TFIIH in the expanded state within the pre-initiation complex | electron microscopy | 2 | — | 3 (best 0.80) |
| 7O4L | Yeast tfiih in the expanded state within the pre-initiation complex | electron microscopy | 2 | — | — |
| 7O72 | Yeast RNA polymerase II transcription pre-initiation complex with closed promoter DNA | electron microscopy | 2 | — | 2 (best 0.82) |
| 7O72 | Yeast RNA polymerase II transcription pre-initiation complex with closed promoter DNA | electron microscopy | 2 | — | — |
| 7O73 | Yeast RNA polymerase II transcription pre-initiation complex with closed distorted promoter DNA | electron microscopy | 2 | — | 2 (best 0.79) |
| 7O73 | Yeast RNA polymerase II transcription pre-initiation complex with closed distorted promoter DNA | electron microscopy | 2 | — | — |
| 7O75 | Yeast RNA polymerase II transcription pre-initiation complex with open promoter DNA | electron microscopy | 2 | — | 2 (best 0.80) |
| 7O75 | Yeast RNA polymerase II transcription pre-initiation complex with open promoter DNA | electron microscopy | 2 | — | — |
| 7ZS9 | Yeast RNA polymerase II transcription pre-initiation complex with the +1 nucleosome (complex A) | electron microscopy | 2 | — | 1 (best 0.80) |
| 7ZSA | Yeast RNA polymerase II transcription pre-initiation complex with the +1 nucleosome and NTP… | electron microscopy | 2 | — | 2 (best 0.77) |
| 7ZSB | Yeast RNA polymerase II transcription pre-initiation complex with the +1 nucleosome and NTP… | electron microscopy | 2 | — | 1 (best 0.80) |
| 8UOQ | Composite map of PIC_delta_TFIIK form2 | electron microscopy | 2 | — | 4 (best 0.86) |
| 8UOT | Composite map of PICdeltaTFIIK form1 | electron microscopy | 2 | — | 2 (best 0.81) |
| Q02939 | AlphaFold monomer V2.0 prediction for general transcription and DNA repair factor iih subunit TFB2… | predicted | A | — | 8 (best 0.69) |
Experiment against prediction
- 7O73 chain 2 against the predicted model Q02939: TM-score 0.97, RMSD 1.49 Å
- 7O73 chain 2 against the predicted model Q02939: TM-score 0.97, RMSD 1.49 Å
- 7O72 chain 2 against the predicted model Q02939: TM-score 0.96, RMSD 1.44 Å
- 7O72 chain 2 against the predicted model Q02939: TM-score 0.96, RMSD 1.44 Å
- 7O4J chain 2 against the predicted model Q02939: TM-score 0.96, RMSD 1.55 Å
- 7O4J chain 2 against the predicted model Q02939: TM-score 0.96, RMSD 1.55 Å
- 7O4L chain 2 against the predicted model Q02939: TM-score 0.96, RMSD 1.57 Å
- 7O4L chain 2 against the predicted model Q02939: TM-score 0.96, RMSD 1.57 Å
- 7ZSA chain 2 against the predicted model Q02939: TM-score 0.96, RMSD 1.67 Å
- 7O4I chain 2 against the predicted model Q02939: TM-score 0.96, RMSD 1.66 Å
Elsewhere
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