UniProt Q02574
DNA damage checkpoint control protein MEC3 (Q02574)
DNA damage checkpoint control protein MEC3 (UniProt Q02574): 10 experimental structures and 1 predicted model on GenesisL1, 17 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q02574
- Protein
- DNA damage checkpoint control protein MEC3
- Experimental structures
- 10
- Predicted models
- 1
- Pockets
- 17 · 7 records with a druggable one
Structures
11 records of Q02574 in the MolNFT archive: 10 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 7ST9 | Open state of Rad24-RFC:9-1-1 bound to a 5' ss/dsDNA junction | electron microscopy | H | — | 2 (best 0.77) |
| 7ST9 | Open state of RAD24-RFC:9-1-1 bound to a 5' SS/DSDNA junction | electron microscopy | H | — | — |
| 7STB | Closed state of Rad24-RFC:9-1-1 bound to a 5' ss/dsDNA junction | electron microscopy | H | — | 2 (best 0.78) |
| 7STB | Closed state of RAD24-RFC:9-1-1 bound to a 5' SS/DSDNA junction | electron microscopy | H | — | — |
| 8DQW | Open state of Rad24-RFC:9-1-1 bound to a 5' ss/dsDNA junction | electron microscopy | H | — | 2 (best 0.77) |
| 8DQW | Open state of RAD24-RFC:9-1-1 bound to a 5' SS/DSDNA junction | electron microscopy | H | — | — |
| 8FS4 | Structure of S. cerevisiae Rad24-RFC loading the 9-1-1 clamp onto a 10-nt gapped DNA in step 2… | electron microscopy | F | — | 2 (best 0.80) |
| 8FS6 | Structure of S. cerevisiae Rad24-RFC loading the 9-1-1 clamp onto a 10-nt gapped DNA in step 4… | electron microscopy | F | — | 3 (best 0.82) |
| 8FS7 | Structure of S. cerevisiae Rad24-RFC loading the 9-1-1 clamp onto a 10-nt gapped DNA in step 5… | electron microscopy | F | — | 2 (best 0.77) |
| 8FS8 | Structure of S. cerevisiae Rad24-RFC loading the 9-1-1 clamp onto a 5-nt gapped DNA (9-1-1… | electron microscopy | F | — | 4 (best 0.77) |
| Q02574 | AlphaFold monomer V2.0 prediction for DNA damage checkpoint control protein MEC3 (Q02574) | predicted | A | — | — |
Experiment against prediction
- 8FS6 chain F against the predicted model Q02574: TM-score 0.92, RMSD 1.91 Å
- 8FS7 chain F against the predicted model Q02574: TM-score 0.92, RMSD 1.96 Å
- 8FS8 chain F against the predicted model Q02574: TM-score 0.91, RMSD 2.08 Å
- 7STB chain H against the predicted model Q02574: TM-score 0.90, RMSD 2.32 Å
- 7STB chain H against the predicted model Q02574: TM-score 0.90, RMSD 2.32 Å
- 8FS4 chain F against the predicted model Q02574: TM-score 0.89, RMSD 2.63 Å
- 8DQW chain H against the predicted model Q02574: TM-score 0.86, RMSD 2.92 Å
- 8DQW chain H against the predicted model Q02574: TM-score 0.86, RMSD 2.92 Å
- 7ST9 chain H against the predicted model Q02574: TM-score 0.86, RMSD 2.93 Å
- 7ST9 chain H against the predicted model Q02574: TM-score 0.86, RMSD 2.93 Å
Elsewhere
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.