UniProt Q02487
Desmocollin-2 (Q02487)
Desmocollin-2 (UniProt Q02487): 5 experimental structures and 1 predicted model on GenesisL1, 5 ligands bound, 17 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q02487
- Protein
- Desmocollin-2
- Experimental structures
- 5
- Predicted models
- 1
- Ligands
- 5
- Pockets
- 17 · 2 records with a druggable one
Structures
6 records of Q02487 in the MolNFT archive: 5 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 5ERP | Crystal structure of human Desmocollin-2 ectodomain fragment EC2-5 | x-ray diffraction | A, B | NAG, MAN, CA, SO4 | — |
| 5ERP | Crystal structure of human desmocollin-2 ectodomain fragment EC2-5 | x-ray diffraction | A, B | — | — |
| 5J5J | Crystal structure of a chimera of human Desmocollin-2 EC1 and human Desmoglein-2 EC2-EC5 | x-ray diffraction | A | NAG, MAN, CA, CL | 1 (best 0.50) |
| 5J5J | Crystal structure of a chimera of human desmocollin-2 EC1 and human desmoglein-2 EC2-EC5 | x-ray diffraction | A | — | — |
| 7A7D | Cadherin fit into cryo-ET map | electron microscopy | a, b, c, d, e, f, g | — | 16 (best 0.68) |
| Q02487 | AlphaFold monomer V2.0 prediction for desmocollin-2 (Q02487) | predicted | A | — | — |
Ligands
Experiment against prediction
- 5ERP chain A against the predicted model Q02487: TM-score 0.88, RMSD 2.96 Å
- 5ERP chain A against the predicted model Q02487: TM-score 0.88, RMSD 2.96 Å
- 5J5J chain A against the predicted model Q14126: TM-score 0.83, RMSD 4.00 Å
- 5J5J chain A against the predicted model Q14126: TM-score 0.83, RMSD 4.00 Å
- 5ERP chain B against the predicted model Q02487: TM-score 0.80, RMSD 4.23 Å
- 5ERP chain B against the predicted model Q02487: TM-score 0.80, RMSD 4.23 Å
- 5J5J chain A against the predicted model Q02487: TM-score 0.75, RMSD 4.33 Å
- 5J5J chain A against the predicted model Q02487: TM-score 0.75, RMSD 4.33 Å
- 7A7D chain b against the predicted model Q02487: TM-score 0.66, RMSD 4.24 Å
- 7A7D chain f against the predicted model Q02487: TM-score 0.65, RMSD 4.18 Å
Elsewhere
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