UniProt Q02046
Methylenetetrahydrofolate dehydrogenase [NAD(+)] (Q02046)
Methylenetetrahydrofolate dehydrogenase [NAD(+)] (UniProt Q02046): 4 experimental structures and 1 predicted model on GenesisL1, 5 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q02046
- Protein
- Methylenetetrahydrofolate dehydrogenase [NAD(+)]
- Experimental structures
- 4
- Predicted models
- 1
- Pockets
- 5 · 1 record with a druggable one
Structures
5 records of Q02046 in the MolNFT archive: 4 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1EDZ | Structure of the NAD-dependent 5,10-methylenetetrahydrofolate dehydrogenase from saccharomyces… | x-ray diffraction | A | — | — |
| 1EDZ | Structure of the NAD-dependent 5,10- methylenetetrahydrofolate dehydrogenase from saccharomyces… | x-ray diffraction | A | — | — |
| 1EE9 | Crystal structure of the NAD-dependent 5,10-methylenetetrahydrofolate dehydrogenase from… | x-ray diffraction | A | — | — |
| 1EE9 | Crystal structure of the NAD-dependent 5,10-methylenetetrahydrofolate dehydrogenase from… | x-ray diffraction | A | — | — |
| Q02046 | AlphaFold monomer V2.0 prediction for methylenetetrahydrofolate dehydrogenase [NAD(+)] (Q02046) | predicted | A | — | 5 (best 0.73) |
Experiment against prediction
- 1EE9 chain A against the predicted model Q02046: TM-score 0.98, RMSD 0.93 Å
- 1EE9 chain A against the predicted model Q02046: TM-score 0.98, RMSD 0.93 Å
- 1EDZ chain A against the predicted model Q02046: TM-score 0.98, RMSD 0.95 Å
- 1EDZ chain A against the predicted model Q02046: TM-score 0.98, RMSD 0.95 Å
Elsewhere
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