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UniProt Q01973

Inactive tyrosine-protein kinase transmembrane receptor ROR1 (Q01973)

Inactive tyrosine-protein kinase transmembrane receptor ROR1 (UniProt Q01973): 7 experimental structures on GenesisL1, 1 ligand bound. Binding sites, pockets, druggability and 3D structures in GL1X.

UniProt
Q01973
Protein
Inactive tyrosine-protein kinase transmembrane receptor ROR1
Experimental structures
7
Predicted models
0
Ligands
1

Structures

7 records of Q01973 in the MolNFT archive: 7 experimental, 0 predicted.

EntryTitleMethodChainsLigandsPockets
5Z55NMR solution structure of the kringle domain of human receptor tyrosine kinase-like orphan receptor…solution nmrA——
6BA5Potent and selective antitumor activity of a T-cell engaging bispecific antibody targeting a…x-ray diffractionM, N, O, P——
6BANPotent and selective antitumor activity of a T-cell engaging bispecific antibody targeting a…x-ray diffractionM, N, O, P——
6TU9The ROR1 pseudokinase domain bound to ponatinibx-ray diffractionA, B0LI—
7TNGKringle domain of human Receptor Tyrosine Kinase-Like Orphan Receptor 1 (ROR1)x-ray diffractionA——
7TNGKringle domain of human receptor tyrosine kinase-like orphan receptor 1 (ROR1)x-ray diffractionA——
Q01973AlphaFold monomer V2.0 prediction for inactive tyrosine-protein kinase transmembrane receptor ROR1…———

Ligands

  • 0LI · 3-(imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methyl-N-{4-[(4-methylpiperazin-1-yl)methyl]-3-(trifluoromethyl) phenyl}benzamide · in 1 record

Elsewhere

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