UniProt Q01813
ATP-dependent 6-phosphofructokinase, platelet type (Q01813)
ATP-dependent 6-phosphofructokinase, platelet type (UniProt Q01813), EC 2.7.1.11: 12 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound, 31 pockets. Binding sites, druggability and experiment against…
- UniProt
- Q01813
- Protein
- ATP-dependent 6-phosphofructokinase, platelet type
- EC
- 2.7.1.11
- Experimental structures
- 12
- Predicted models
- 1
- Ligands
- 2
- Pockets
- 31 · 2 records with a druggable one
Structures
13 records of Q01813 in the MolNFT archive: 12 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 4RH3 | AMPPCP-bound structure of human platelet phosphofructokinase in an R-state, crystal form II | x-ray diffraction | A, B, C, D | — | — |
| 4RH3 | Amppcp-bound structure of human platelet phosphofructokinase in an R- state, crystal form II | x-ray diffraction | A, B, C, D | — | — |
| 4U1R | ATP-bound structure of human platelet phosphofructokinase in an R-state, crystal form II | x-ray diffraction | A, B, C, D | — | — |
| 4U1R | ATP-bound structure of human platelet phosphofructokinase in an R- state, crystal form II | x-ray diffraction | A, B, C, D | — | — |
| 4WL0 | Ligand-free structure of human platelet phosphofructokinase in an R- state, crystal form I | x-ray diffraction | A, B, C, D | — | — |
| 4XYJ | Crystal structure of human phosphofructokinase-1 in complex with ATP and Mg, Northeast Structural… | x-ray diffraction | A, B, C, D, E, F, G, H | — | — |
| 4XYJ | Crystal structure of human phosphofructokinase-1 in complex with ATP and mg, northeast structural… | x-ray diffraction | A, B, C, D, E, F, G, H | — | — |
| 4XYK | Crystal structure of human phosphofructokinase-1 in complex with ADP, Northeast Structural Genomics… | x-ray diffraction | A, B, C, D | — | — |
| 4XYK | Crystal structure of human phosphofructokinase-1 in complex with ADP, northeast structural genomics… | x-ray diffraction | A, B, C, D | — | — |
| 4XZ2 | Human platelet phosphofructokinase in an R-state in complex with ADP and F6P, crystal form I | x-ray diffraction | A, B, C, D | — | — |
| 4XZ2 | Human platelet phosphofructokinase in an R-state in complex with ADP and F6P, crystal form I | x-ray diffraction | A, B, C, D | — | — |
| 7TFF | Crystal structure of human platelet phosphofructokinase-1 mutant- D564N | x-ray diffraction | A, B, C, D | PO4, SO4 | 20 (best 0.86) |
| Q01813 | AlphaFold monomer V2.0 prediction for ATP-dependent 6-phosphofructokinase, platelet type (Q01813) | predicted | A | — | 11 (best 0.80) |
Ligands
Experiment against prediction
- 4XZ2 chain B against the predicted model Q01813: TM-score 1.00, RMSD 0.44 Å
- 4XZ2 chain B against the predicted model Q01813: TM-score 1.00, RMSD 0.44 Å
- 4XZ2 chain D against the predicted model Q01813: TM-score 1.00, RMSD 0.48 Å
- 4XZ2 chain D against the predicted model Q01813: TM-score 1.00, RMSD 0.48 Å
- 4RH3 chain A against the predicted model Q01813: TM-score 1.00, RMSD 0.50 Å
- 4RH3 chain A against the predicted model Q01813: TM-score 1.00, RMSD 0.50 Å
- 4U1R chain A against the predicted model Q01813: TM-score 1.00, RMSD 0.51 Å
- 4U1R chain A against the predicted model Q01813: TM-score 1.00, RMSD 0.51 Å
- 4XZ2 chain C against the predicted model Q01813: TM-score 1.00, RMSD 0.52 Å
- 4XZ2 chain C against the predicted model Q01813: TM-score 1.00, RMSD 0.52 Å
Elsewhere
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