UniProt Q01782
Q01782
Q01782 (UniProt Q01782): 22 experimental structures on GenesisL1, 4 ligands bound. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- Q01782
- Experimental structures
- 22
- Predicted models
- 0
- Ligands
- 4
Structures
22 records of Q01782 in the MolNFT archive: 22 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1W0C | Inhibition of Leishmania major pteridine reductase (PTR1) by 2,4,6-triaminoquinazoline; structure… | x-ray diffraction | A, B, C, D, E, F, G, H | — | — |
| 1W0C | Inhibition of leishmania major pteridine reductase (PTR1) by 2,4,6-triaminoquinazoline; structure… | x-ray diffraction | A, B, C, D, E, F, G, H | — | — |
| 2BF7 | Leishmania major pteridine reductase 1 in complex with NADP and biopterin | x-ray diffraction | A, B, C, D | — | — |
| 2BF7 | Leishmania major pteridine reductase 1 in complex with NADP and biopterin | x-ray diffraction | A, B, C, D | — | — |
| 2BFA | Leishmania major pteridine reductase 1 in complex with NADP and CB3717 | x-ray diffraction | A, B, C, D | — | — |
| 2BFA | Leishmania major pteridine reductase 1 in complex with NADP and CB3717 | x-ray diffraction | A, B, C, D | — | — |
| 2BFM | Leishmania major pteridine reductase 1 in complex with NADP and trimethoprim | x-ray diffraction | A, B, C, D | — | — |
| 2BFM | Leishmania major pteridine reductase 1 in complex with NADP and trimethoprim | x-ray diffraction | A, B, C, D | — | — |
| 2BFO | Leishmania major pteridine reductase 1 in complex with NADPH | x-ray diffraction | A, B, C, D | — | — |
| 2BFO | Leishmania major pteridine reductase 1 in complex with NADPH | x-ray diffraction | A, B, C, D | — | — |
| 2BFP | Leishmania major pteridine reductase 1 in complex with NADP and tetrahydrobiopterin | x-ray diffraction | A, B, C, D | — | — |
| 2BFP | Leishmania major pteridine reductase 1 in complex with NADP and tetrahydrobiopterin | x-ray diffraction | A, B, C, D | — | — |
| 2QHX | Structure of Pteridine Reductase from Leishmania major complexed with a ligand | x-ray diffraction | A, B, C, D | — | — |
| 2QHX | Structure of pteridine reductase from leishmania major complexed with a ligand | x-ray diffraction | A, B, C, D | — | — |
| 3H4V | Selective screening and design to identify inhibitors of leishmania major pteridine reductase 1 | x-ray diffraction | A, B, C, D, E, F, G, H | — | — |
| 3H4V | Selective screening and design to identify inhibitors of leishmania major pteridine reductase 1 | x-ray diffraction | A, B, C, D, E, F, G, H | — | — |
| 5L42 | Leishmania major pteridine reductase 1 (PTR1) in complex with compound 3 | x-ray diffraction | A, B, C, D | 6J6, NDP | — |
| 5L4N | Leishmania major Pteridine reductase 1 (PTR1) in complex with compound 1 | x-ray diffraction | A, B, C, D | 6QT, NDP | — |
| 5L4N | Leishmania major pteridine reductase 1 (PTR1) in complex with compound 1 | x-ray diffraction | A, B, C, D | 6QT, NDP | — |
| 6RXC | Leishmania major pteridine reductase 1 (LMPTR1) in complex with inhibitor 4 (nmt-C0026) | x-ray diffraction | A, B, C, D | NDP, KMK | — |
| 7PXX | The crystal structure of leishmania major pteridine reductase 1 in complex with substrate folic acid | x-ray diffraction | A, B, C, D | NDP | — |
| Q01782 | AlphaFold monomer V2.0 prediction for pteridine reductase 1 (Q01782) | — | — | — |
Ligands
- NDP · Nadph dihydro-nicotinamide-adenine-dinucleotide phosphate · in 5 records
- 6QT · (2~{R})-2-(3-hydroxyphenyl)-6-oxidanyl-2,3-dihydrochromen-4-one · in 2 records
- 6J6 · (2~{R})-2-[3,4-bis(oxidanyl)phenyl]-6-oxidanyl-2,3-dihydrochromen-4-one · in 1 record
- KMK · Methyl 1-[4-[[2,4-bis(azanyl)pteridin-6-yl]methyl-(3-oxidanylpropyl)amino]phenyl]carbonylpiperidine-4-carboxylate · in 1 record
Elsewhere
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.