UniProt Q01454
DNA polymerase alpha-binding protein (Q01454)
DNA polymerase alpha-binding protein (UniProt Q01454): 25 experimental structures and 1 predicted model on GenesisL1, 30 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q01454
- Protein
- DNA polymerase alpha-binding protein
- Experimental structures
- 25
- Predicted models
- 1
- Pockets
- 30 · 8 records with a druggable one
Structures
26 records of Q01454 in the MolNFT archive: 25 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 4C8H | Crystal structure of the C-terminal region of yeast Ctf4, selenomethionine protein. | x-ray diffraction | A, B, C | — | — |
| 4C8H | Crystal structure of the C-terminal region of yeast CTF4, selenomethionine protein. | x-ray diffraction | A, B, C | — | — |
| 4C8S | Crystal structure of the C-terminal region of yeast Ctf4 | x-ray diffraction | A, B, C | — | — |
| 4C8S | Crystal structure of the C-terminal region of yeast CTF4 | x-ray diffraction | A, B, C | — | — |
| 4C93 | Crystal structure of the carboxy-terminal domain of yeast Ctf4 bound to Pol alpha. | x-ray diffraction | A, B, C | — | — |
| 4C93 | Crystal structure of the carboxy-terminal domain of yeast CTF4 bound to pol alpha. | x-ray diffraction | A, B, C | — | — |
| 4C95 | Crystal structure of the carboxy-terminal domain of yeast Ctf4 bound to Sld5 | x-ray diffraction | A, B, C | — | — |
| 4C95 | Crystal structure of the carboxy-terminal domain of yeast CTF4 bound to SLD5 | x-ray diffraction | A, B, C | — | — |
| 5HOG | Crystal structure of the carboxy-terminal domain of yeast Ctf4 bound to Dna2. | x-ray diffraction | A, B, C | — | — |
| 5HOG | Crystal structure of the carboxy-terminal domain of yeast CTF4 bound to DNA2. | x-ray diffraction | A, B, C | — | — |
| 5HOI | Crystal structure of the carboxy-terminal domain of yeast Ctf4 bound to Tof2. | x-ray diffraction | A, B, C | — | 18 (best 0.81) |
| 5HOI | Crystal structure of the carboxy-terminal domain of yeast CTF4 bound to TOF2. | x-ray diffraction | A, B, C | — | — |
| 5NXQ | Crystal structure of the carboxy-terminal domain of yeast Ctf4 bound to a stapled Sld5 CIP | x-ray diffraction | A, B, C | — | — |
| 5NXQ | Crystal structure of the carboxy-terminal domain of yeast CTF4 bound to a stapled SLD5 cip | x-ray diffraction | A, B, C | — | — |
| 6PTJ | Structure of Ctf4 trimer in complex with one CMG helicase | electron microscopy | E, F, G | — | — |
| 6PTJ | Structure of CTF4 trimer in complex with one cmg helicase | electron microscopy | E, F, G | — | — |
| 6PTN | Structure of CTF4 trimer in complex with two cmg helicases | electron microscopy | E, F, G | — | — |
| 6PTO | Structure of Ctf4 trimer in complex with three CMG helicases | electron microscopy | X, Y, Z | — | 1 (best 0.87) |
| 6SKL | Cryo-EM structure of the CMG Fork Protection Complex at a replication fork - Conformation 1 | electron microscopy | F, G, H | — | 2 (best 0.79) |
| 7PMN | S. cerevisiae replisome-SCF(Dia2) complex bound to double-stranded DNA (conformation II) | electron microscopy | F, G, H | — | 2 (best 0.78) |
| 8B9A | S. cerevisiae replisome + Ctf4, bound by pol alpha primase. Complex engaged with a fork DNA… | electron microscopy | H, L, K | — | 2 (best 0.81) |
| 8B9B | S. cerevisiae replisome + Ctf4, bound by pol alpha. Complex engaged with a fork DNA substrate… | electron microscopy | H, L, K | — | — |
| 8KG6 | Yeast replisome in state I | electron microscopy | F, G, H | — | 1 (best 0.80) |
| 8KG9 | Yeast replisome in state III | electron microscopy | F, G, H | — | 2 (best 0.84) |
| 8W7M | Yeast replisome in state V | electron microscopy | F, G, H | — | 2 (best 0.78) |
| Q01454 | AlphaFold monomer V2.0 prediction for DNA polymerase alpha-binding protein (Q01454) | predicted | A | — | — |
Experiment against prediction
- 5NXQ chain B against the predicted model Q01454: TM-score 1.00, RMSD 0.23 Å
- 5NXQ chain B against the predicted model Q01454: TM-score 1.00, RMSD 0.23 Å
- 5HOI chain B against the predicted model Q01454: TM-score 1.00, RMSD 0.27 Å
- 5HOI chain B against the predicted model Q01454: TM-score 1.00, RMSD 0.27 Å
- 4C8S chain B against the predicted model Q01454: TM-score 1.00, RMSD 0.27 Å
- 4C8S chain B against the predicted model Q01454: TM-score 1.00, RMSD 0.27 Å
- 4C93 chain B against the predicted model Q01454: TM-score 1.00, RMSD 0.28 Å
- 4C93 chain B against the predicted model Q01454: TM-score 1.00, RMSD 0.28 Å
- 5HOG chain B against the predicted model Q01454: TM-score 1.00, RMSD 0.29 Å
- 5HOG chain B against the predicted model Q01454: TM-score 1.00, RMSD 0.29 Å
Elsewhere
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