UniProt P9WPC2
ATP-dependent Clp protease proteolytic subunit 2 (P9WPC2)
ATP-dependent Clp protease proteolytic subunit 2 (UniProt P9WPC2), EC 3.4.21.92: 7 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound, 16 pockets. Binding sites, druggability and experiment against…
- UniProt
- P9WPC2
- Protein
- ATP-dependent Clp protease proteolytic subunit 2
- EC
- 3.4.21.92
- Experimental structures
- 7
- Predicted models
- 1
- Ligands
- 2
- Pockets
- 16 · 1 record with a druggable one
Structures
8 records of P9WPC2 in the MolNFT archive: 7 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 5DZK | Crystal structure of the active form of the proteolytic complex clpP1 and clpP2 | x-ray diffraction | A, B, C, D, E, F, G, a, b, c, d, e, f, g | — | — |
| 5DZK | Crystal structure of the active form of the proteolytic complex CLPP1 and CLPP2 | x-ray diffraction | A, B, C, D, E, F, G, a, b, c, d, e, f, g | — | — |
| 5E0S | crystal structure of the active form of the proteolytic complex clpP1 and clpP2 | x-ray diffraction | A, B, C, D, E, F, G, a, b, c, d, e, f, g | — | — |
| 5E0S | Crystal structure of the active form of the proteolytic complex CLPP1 and CLPP2 | x-ray diffraction | A, B, C, D, E, F, G, a, b, c, d, e, f, g | — | — |
| 6IW7 | structural insights into Mycobacterium tuberculosis ClpP1P2 inhibition by Cediranib: implications… | x-ray diffraction | A, C, F, H, J, L, E | — | — |
| 6IW7 | Structural insights into mycobacterium tuberculosis CLPP1P2 inhibition by cediranib: implications… | x-ray diffraction | A, C, F, H, J, L, E | BEZ | — |
| 7X8X | structural insights into Mycobacterium tuberculosis ClpP1P2 inhibition by Cediranib: implications… | x-ray diffraction | A, O, C, Q, F, S, H, T, J, V, L, X, E, a | AI4 | 16 (best 0.74) |
| P9WPC2 | AlphaFold monomer V2.0 prediction for ATP-dependent clp protease proteolytic subunit 2 (P9WPC2) | predicted | A | — | — |
Ligands
Experiment against prediction
- 6IW7 chain L against the predicted model P9WPC2: TM-score 1.00, RMSD 0.35 Å
- 6IW7 chain E against the predicted model P9WPC2: TM-score 1.00, RMSD 0.35 Å
- 6IW7 chain A against the predicted model P9WPC2: TM-score 1.00, RMSD 0.36 Å
- 6IW7 chain H against the predicted model P9WPC2: TM-score 0.99, RMSD 0.38 Å
- 6IW7 chain C against the predicted model P9WPC2: TM-score 0.99, RMSD 0.38 Å
- 7X8X chain L against the predicted model P9WPC2: TM-score 0.99, RMSD 0.39 Å
- 7X8X chain A against the predicted model P9WPC2: TM-score 0.99, RMSD 0.40 Å
- 7X8X chain E against the predicted model P9WPC2: TM-score 0.99, RMSD 0.41 Å
- 7X8X chain a against the predicted model P9WPC2: TM-score 0.99, RMSD 0.41 Å
- 7X8X chain O against the predicted model P9WPC2: TM-score 0.99, RMSD 0.42 Å
Elsewhere
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.