UniProt P9WN67
UDP-glucose 4-epimerase (P9WN67)
UDP-glucose 4-epimerase (UniProt P9WN67), EC 5.1.3.2: 7 experimental structures and 1 predicted model on GenesisL1, 4 ligands bound, 15 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P9WN67
- Protein
- UDP-glucose 4-epimerase
- EC
- 5.1.3.2
- Experimental structures
- 7
- Predicted models
- 1
- Ligands
- 4
- Pockets
- 15 · 5 records with a druggable one
Structures
8 records of P9WN67 in the MolNFT archive: 7 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 6LTT | Crystal structure of udp-glucose 4-epimerase GALE1 from mycobacterium tuberculosis | x-ray diffraction | A, B | NAD | — |
| 7YS8 | Crystal Structure of UDP-glucose 4-epimerase (Rv3634c) from Mycobacterium tuberculosis | x-ray diffraction | A, B | NAD | 3 (best 0.84) |
| 7YS9 | Crystal Structure of UDP-glucose 4-epimerase (Rv3634c) in complex with both UDP-Glucose and… | x-ray diffraction | A, B | NAD, UPG, GDU | 3 (best 0.84) |
| 7YSA | Crystal Structure of UDP-glucose 4-epimerase (Rv3634c) in complex with UDP-glucose in chain A and… | x-ray diffraction | A, B | NAD, UPG, GDU | 3 (best 0.85) |
| 7YSM | Crystal Structure of UDP-glucose 4-epimerase (Rv3634c) co-crystallized with UDP-N-acetylglucosamine… | x-ray diffraction | A, B | NAD, UD2 | 3 (best 0.84) |
| 7YSY | Crystal Structure of UDP-glucose 4-epimerase (Rv3634c) co-crystallized with… | x-ray diffraction | A, B | NAD, UD2 | — |
| 7YT0 | Crystal Structure of UDP-glucose 4-epimerase (Rv3634c) in complex with UDP-galactose from… | x-ray diffraction | A, B | NAD, GDU | 3 (best 0.84) |
| P9WN67 | AlphaFold monomer V2.0 prediction for udp-glucose 4-epimerase (P9WN67) | predicted | A | — | — |
Ligands
Experiment against prediction
- 6LTT chain B against the predicted model P9WN67: TM-score 0.99, RMSD 0.57 Å
- 7YS8 chain B against the predicted model P9WN67: TM-score 0.99, RMSD 0.57 Å
- 7YT0 chain A against the predicted model P9WN67: TM-score 0.98, RMSD 1.05 Å
- 7YS8 chain A against the predicted model P9WN67: TM-score 0.98, RMSD 1.07 Å
- 6LTT chain A against the predicted model P9WN67: TM-score 0.98, RMSD 1.07 Å
- 7YT0 chain B against the predicted model P9WN67: TM-score 0.98, RMSD 1.07 Å
- 7YSY chain B against the predicted model P9WN67: TM-score 0.98, RMSD 1.07 Å
- 7YSM chain A against the predicted model P9WN67: TM-score 0.98, RMSD 1.07 Å
- 7YSM chain B against the predicted model P9WN67: TM-score 0.97, RMSD 1.07 Å
- 7YSA chain B against the predicted model P9WN67: TM-score 0.97, RMSD 1.07 Å
Elsewhere
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