UniProt P9WJF1
Decaprenylphosphoryl-beta-D-ribose oxidase (P9WJF1)
Decaprenylphosphoryl-beta-D-ribose oxidase (UniProt P9WJF1), EC 1.-.-.-, 1.1.98.3: 17 experimental structures and 1 predicted model on GenesisL1, 9 ligands bound, 47 pockets. Binding sites, druggability and experiment against…
- UniProt
- P9WJF1
- Protein
- Decaprenylphosphoryl-beta-D-ribose oxidase
- EC
- 1.-.-.-, 1.1.98.3
- Experimental structures
- 17
- Predicted models
- 1
- Ligands
- 9
- Pockets
- 47 · 9 records with a druggable one
Structures
18 records of P9WJF1 in the MolNFT archive: 17 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 4PFA | Crystal structure of M. tuberculosis in complex with BTO - covalent adduct | x-ray diffraction | A, B | FAD, N77 | 4 (best 0.80) |
| 4PFA | Crystal structure of M. tuberculosis in complex with bto - covalent adduct | x-ray diffraction | A, B | — | — |
| 4PFD | Crystal structure of M. tuberculosis in complex with a cBT - non-covalent adduct | x-ray diffraction | A, B | FAD, 2R2 | 6 (best 0.82) |
| 4PFD | Crystal structure of M. tuberculosis in complex with a cbt - non- covalent adduct | x-ray diffraction | A, B | — | — |
| 5OEP | Mycobacterium tuberculosis DprE1 in complex with inhibitor TCA481 | x-ray diffraction | A, B | FAD, 9T2 | 4 (best 0.80) |
| 5OEP | Mycobacterium tuberculosis DPRE1 in complex with inhibitor TCA481 | x-ray diffraction | A, B | FAD, 9T2 | — |
| 6G83 | Crystal structure of M. tuberculosis DprE1 in complex with sPBTZ169 (sulfonylPBTZ) | x-ray diffraction | A, B | FAD, EQ8 | 5 (best 0.78) |
| 6HEZ | M tuberculosis DprE1 in complex with BTZ043 | x-ray diffraction | A, B | 0SK, FAD | 6 (best 0.81) |
| 6HEZ | M tuberculosis DPRE1 in complex with BTZ043 | x-ray diffraction | A, B | 0SK, FAD | — |
| 6HF0 | M. tuberculosis DprE1 covalently bound to a nitrobenzoxaci . | x-ray diffraction | A, B | FAD, G1H | 5 (best 0.80) |
| 6HF0 | M. tuberculosis DPRE1 covalently bound to a nitrobenzoxacinone. | x-ray diffraction | A, B | FAD, G1H | — |
| 6HF3 | M tuberculosis DprE1 in complex with a covalently bound nitrobenzothiazi | x-ray diffraction | A, B | 26J, FAD | 4 (best 0.80) |
| 6HF3 | M tuberculosis DPRE1 in complex with a covalently bound nitrobenzothiazinone | x-ray diffraction | A, B | 26J, FAD | — |
| 6HFV | Mycobacterium tuberculosis DprE1 in complex with CMP2 | x-ray diffraction | A, B | FAD, G1T | 6 (best 0.82) |
| 6HFV | Mycobacterium tuberculosis DPRE1 in complex with CMP2 | x-ray diffraction | A, B | FAD, G1T | — |
| 6HFW | Mycobacterium tuberculosis DprE1 in complex with CMP1 | x-ray diffraction | A, B | FAD, G1T | 7 (best 0.82) |
| 6HFW | Mycobacterium tuberculosis DPRE1 in complex with CMP1 | x-ray diffraction | A, B | FAD, G1T | — |
| P9WJF1 | AlphaFold monomer V2.0 prediction for decaprenylphosphoryl-beta-D- ribose oxidase (P9WJF1) | predicted | A | — | — |
Ligands
- FAD · Flavin-adenine dinucleotide · in 15 records
- G1T · 8-(oxidanylamino)-2-piperidin-1-yl-6-(trifluoromethyl)-1,3-benzothiazin-4-one · in 4 records
- 0SK · 8-(hydroxyamino)-2-[(2S)-2-methyl-1,4-dioxa-8-azaspiro[4.5]dec-8-yl]-6-(trifluoromethyl)-4H-1,3-benzothiazin-4-one · in 2 records
- 26J · 2-(4-(cyclohexylmethyl)piperazin-1-yl)-8-nitro-6-(trifluoromethyl)-4H-benzo[e][1,3]thiazin-4-one, bound form · in 2 records
- 9T2 · ethyl ~{N}-[2-(1,3-benzothiazol-2-ylcarbonylamino)-5-fluoranyl-thiophen-3-yl]carbonylcarbamate · in 2 records
- G1H · 2-[(2~{S},6~{R})-2,6-dimethylpiperidin-1-yl]-8-nitro-6-(trifluoromethyl)-1,3-benzoxazin-4-one · in 2 records
- 2R2 · [4-(2-methoxyethyl)piperazin-1-yl][6-methyl-7-nitro-5-(trifluoromethyl)-1,3-benzothiazol-2-yl]methanone · in 1 record
- EQ8 · [2-(4-cyclohexylsulfonylpiperazin-1-yl)-4-oxidanylidene-6-(trifluoromethyl)-1,3-benzothiazin-8-yl]-oxidanylidene-azanium · in 1 record
- N77 · 7-(hydroxyamino)-N-(pyridin-3-ylmethyl)-5-(trifluoromethyl)-1,3-benzothiazole-2-carboxamide 3-oxide · in 1 record
Experiment against prediction
- 4PFD chain B against the predicted model P9WJF1: TM-score 0.99, RMSD 0.83 Å
- 4PFD chain B against the predicted model P9WJF1: TM-score 0.99, RMSD 0.83 Å
- 6G83 chain B against the predicted model P9WJF1: TM-score 0.98, RMSD 1.15 Å
- 5OEP chain B against the predicted model P9WJF1: TM-score 0.98, RMSD 1.11 Å
- 5OEP chain B against the predicted model P9WJF1: TM-score 0.98, RMSD 1.11 Å
- 4PFA chain B against the predicted model P9WJF1: TM-score 0.98, RMSD 1.33 Å
- 4PFA chain B against the predicted model P9WJF1: TM-score 0.98, RMSD 1.33 Å
- 6HF0 chain B against the predicted model P9WJF1: TM-score 0.98, RMSD 1.14 Å
- 6HF0 chain B against the predicted model P9WJF1: TM-score 0.98, RMSD 1.14 Å
- 4PFD chain A against the predicted model P9WJF1: TM-score 0.98, RMSD 1.50 Å
Elsewhere
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.