UniProt P9WHQ9
Hypoxanthine-guanine phosphoribosyltransferase (P9WHQ9)
Hypoxanthine-guanine phosphoribosyltransferase (UniProt P9WHQ9), EC 2.4.2.8: 7 experimental structures on GenesisL1, 5 ligands bound, 7 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- P9WHQ9
- Protein
- Hypoxanthine-guanine phosphoribosyltransferase
- EC
- 2.4.2.8
- Experimental structures
- 7
- Predicted models
- 0
- Ligands
- 5
- Pockets
- 7 · 1 record with a druggable one
Structures
7 records of P9WHQ9 in the MolNFT archive: 7 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 5KNP | Crystal structure of Mycobacterium tuberculosis hypoxanthine guanine phosphoribosyltransferase in… | x-ray diffraction | A, B, C, D | 6W7, MG, POP | 7 (best 0.70) |
| 5KNP | Crystal structure of mycobacterium tuberculosis hypoxanthine guanine phosphoribosyltransferase in… | x-ray diffraction | A, B, C, D | 6W7, MG, POP | — |
| 5KNQ | Crystal structure of Mycobacterium tuberculosis hypoxanthine guanine phosphoribosyltransferase in… | x-ray diffraction | A, B, C, D | 6W8, MG, POP | — |
| 5KNQ | Crystal structure of mycobacterium tuberculosis hypoxanthine guanine phosphoribosyltransferase in… | x-ray diffraction | A, B, C, D | 6W8, MG, POP | — |
| 5KNY | Crystal structure of Mycobacterium tuberculosis hypoxanthine guanine phosphoribosyltransferase in… | x-ray diffraction | A, B, C, D | YPG, MG | — |
| 5KNY | Crystal structure of mycobacterium tuberculosis hypoxanthine guanine phosphoribosyltransferase in… | x-ray diffraction | A, B, C, D | YPG, MG | — |
| P9WHQ9 | AlphaFold monomer V2.0 prediction for hypoxanthine-guanine phosphoribosyltransferase (P9WHQ9) | — | — | — |
Ligands
- MG · Magnesium ion · in 6 records
- POP · Pyrophosphate 2- · in 4 records
- 6W7 · [(3~{S},4~{R})-4-(6-oxidanylidene-1~{H}-purin-9-yl) pyrrolidin-3-yl]oxymethylphosphonic acid · in 2 records
- 6W8 · [(3~{S},4~{R})-4-(2-azanyl-6-oxidanylidene-1~{H}-purin-9-yl)pyrrolidin-3-yl]oxymethylphosphonic acid · in 2 records
- YPG · [3-[(3~{R},4~{R})-3-(2-azanyl-6-oxidanylidene-1~{H}-purin-9-yl)-4-[(2~{S})-2-oxidanyl-2-phosphono-ethoxy]pyrrolidin-1-yl]-3-oxidanylidene-propyl]phosphonic acid · in 2 records
Elsewhere
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