UniProt P9WGU9
Trehalose-binding lipoprotein LpqY (P9WGU9)
Trehalose-binding lipoprotein LpqY (UniProt P9WGU9): 6 experimental structures and 1 predicted model on GenesisL1, 5 ligands bound, 17 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P9WGU9
- Protein
- Trehalose-binding lipoprotein LpqY
- Experimental structures
- 6
- Predicted models
- 1
- Ligands
- 5
- Pockets
- 17 · 4 records with a druggable one
Structures
7 records of P9WGU9 in the MolNFT archive: 6 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 7WCJ | Crystal structure lpqy from mycobacterium tuberculosis | x-ray diffraction | A, B | SO4 | — |
| 7WDA | Crystal structure LpqY in complex with Trehalose from Mycobacterium tuberculosis | x-ray diffraction | A, B, C, D | GLC, SO4 | — |
| 7WDA | Crystal structure lpqy in complex with trehalose from mycobacterium tuberculosis | x-ray diffraction | A, B, C, D | GLC, SO4 | — |
| 8JAA | Crystal structure of Mycobacterium tuberculosis LpqY in complex with trehalose analogue YB-04 | x-ray diffraction | A | SO4, TY6 | 5 (best 0.77) |
| 8JAB | Crystal structure of Mycobacterium tuberculosis LpqY in complex with trehalose analogue YB-06 | x-ray diffraction | A | U0X, SO4 | 4 (best 0.74) |
| 8JAC | Crystal structure of Mycobacterium tuberculosis LpqY in complex with trehalose analogue YB-16 | x-ray diffraction | A | SO4, W4Z, GLC | 4 (best 0.76) |
| P9WGU9 | AlphaFold monomer V2.0 prediction for trehalose-binding lipoprotein lpqy (P9WGU9) | predicted | A | — | 4 (best 0.65) |
Ligands
- SO4 · Sulfate ion · in 6 records
- GLC · alpha-D-glucopyranose · in 3 records
- TY6 · (2~{S},3~{R},4~{S},5~{S},6~{S})-6-[(2-azanylhydrazinyl)methyl]oxane-2,3,4,5-tetrol · in 1 record
- U0X · (2~{S},3~{S},4~{R},5~{S},6~{R})-2-(fluoranylmethyl)-6-[(2~{R},3~{R},4~{S},5~{S},6~{S})-6-(fluoranylmethyl)-3,4,5-tris(oxidanyl)oxan-2-yl]oxy-oxane-3,4,5-triol · in 1 record
- W4Z · N-[[(2R,3S,4S,5R,6S)-3,4,5,6-tetrakis(oxidanyl)oxan-2-yl]methyl]ethanamide · in 1 record
Experiment against prediction
- 7WDA chain D against the predicted model P9WGU9: TM-score 0.99, RMSD 0.73 Å
- 7WDA chain D against the predicted model P9WGU9: TM-score 0.99, RMSD 0.73 Å
- 7WDA chain C against the predicted model P9WGU9: TM-score 0.99, RMSD 0.75 Å
- 7WDA chain C against the predicted model P9WGU9: TM-score 0.99, RMSD 0.75 Å
- 7WDA chain A against the predicted model P9WGU9: TM-score 0.98, RMSD 0.98 Å
- 7WDA chain A against the predicted model P9WGU9: TM-score 0.98, RMSD 0.98 Å
- 7WDA chain B against the predicted model P9WGU9: TM-score 0.98, RMSD 1.01 Å
- 7WDA chain B against the predicted model P9WGU9: TM-score 0.98, RMSD 1.01 Å
- 7WCJ chain A against the predicted model P9WGU9: TM-score 0.98, RMSD 0.87 Å
- 8JAA chain A against the predicted model P9WGU9: TM-score 0.95, RMSD 1.82 Å
Elsewhere
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