UniProt P9WFR5
Decaprenyl-phosphate phosphoribosyltransferase (P9WFR5)
Decaprenyl-phosphate phosphoribosyltransferase (UniProt P9WFR5), EC 2.4.2.45: 2 experimental structures and 1 predicted model on GenesisL1, 4 ligands bound, 21 pockets. Binding sites, druggability and experiment against…
- UniProt
- P9WFR5
- Protein
- Decaprenyl-phosphate phosphoribosyltransferase
- EC
- 2.4.2.45
- Experimental structures
- 2
- Predicted models
- 1
- Ligands
- 4
- Pockets
- 21 · 2 records with a druggable one
Structures
3 records of P9WFR5 in the MolNFT archive: 2 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 8J8J | Membrane bound PRTase, C3 symmetry, donor bound | electron microscopy | D, A, B | PRP, MG, PGW | 8 (best 0.78) |
| 8J8K | Membrane bound PRTase, C3 symmetry, acceptor bound | electron microscopy | A, B, C | DSL | 13 (best 0.75) |
| P9WFR5 | AlphaFold monomer V2.0 prediction for decaprenyl-phosphate phosphoribosyltransferase (P9WFR5) | predicted | A | — | — |
Ligands
- DSL · Mono-trans, octa-cis decaprenyl-phosphate · in 1 record
- MG · Magnesium ion · in 1 record
- PGW · (1R)-2-{[(S)-{[(2S)-2,3-dihydroxypropyl]oxy}(hydroxy) phosphoryl]oxy}-1-[(hexadecanoyloxy)methyl]ethyl (9Z)-octadec-9-enoate · in 1 record
- PRP · 1-O-pyrophosphono-5-O-phosphono-alpha-D-ribofuranose · in 1 record
Experiment against prediction
- 8J8J chain A against the predicted model P9WFR5: TM-score 0.96, RMSD 1.31 Å
- 8J8J chain B against the predicted model P9WFR5: TM-score 0.96, RMSD 1.31 Å
- 8J8J chain D against the predicted model P9WFR5: TM-score 0.96, RMSD 1.31 Å
- 8J8K chain B against the predicted model P9WFR5: TM-score 0.94, RMSD 1.65 Å
- 8J8K chain A against the predicted model P9WFR5: TM-score 0.94, RMSD 1.65 Å
- 8J8K chain C against the predicted model P9WFR5: TM-score 0.94, RMSD 1.65 Å
Elsewhere
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