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UniProt P98194

Calcium-transporting ATPase type 2C member 1 (P98194)

Calcium-transporting ATPase type 2C member 1 (UniProt P98194), EC 7.2.2.10: 5 experimental structures and 1 predicted model on GenesisL1, 6 ligands bound, 48 pockets. Binding sites, druggability and experiment against prediction…

UniProt
P98194
Protein
Calcium-transporting ATPase type 2C member 1
EC
7.2.2.10
Experimental structures
5
Predicted models
1
Ligands
6
Pockets
48 · 4 records with a druggable one

Structures

6 records of P98194 in the MolNFT archive: 5 experimental, 1 predicted.

EntryTitleMethodChainsLigandsPockets
7YAHCryoEM structure of SPCA1a in E1-Ca-AMPPCP state subclass 2electron microscopyAACP, CA13 (best 0.85)
7YAICryoEM structure of SPCA1a in E1-Ca-AMPPCP state subclass 3electron microscopyAACP, CA—
7YAJCryoEM structure of SPCA1a in E1-Mn-AMPPCP state subclass 1electron microscopyAACP, MN12 (best 0.85)
8IWUhSPCA1 in the E2~P stateelectron microscopyAMG, ALF11 (best 0.77)
8IWWhSPCA1 in the CaE1P-ADP stateelectron microscopyACA, ADP, ALF12 (best 0.73)
P98194AlphaFold monomer V2.0 prediction for calcium-transporting ATPase type 2C member 1 (P98194)predictedA——

Ligands

  • ACP · Phosphomethylphosphonic acid adenylate ester · in 3 records
  • CA · Calcium ion · in 3 records
  • ALF · Tetrafluoroaluminate ion · in 2 records
  • ADP · Adenosine-5'-diphosphate · in 1 record
  • MG · Magnesium ion · in 1 record
  • MN · Manganese (II) ion · in 1 record

Experiment against prediction

Elsewhere

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