UniProt P98082
Disabled homolog 2 (P98082)
Disabled homolog 2 (UniProt P98082): 5 experimental structures and 1 predicted model on GenesisL1, 3 ligands bound, 1 pocket. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P98082
- Protein
- Disabled homolog 2
- Experimental structures
- 5
- Predicted models
- 1
- Ligands
- 3
- Pockets
- 1 · 1 record with a druggable one
Structures
6 records of P98082 in the MolNFT archive: 5 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2LSW | Structure, sulfatide-binding properties, and inhibition of platelet aggregation by a… | solution nmr | A | — | — |
| 2LSW | Structure, sulfatide-binding properties, and inhibition of platelet aggregation by a… | solution nmr | A | — | — |
| 6O5O | Crystal structure of the disabled-2 (DAB2) dab homology domain in complex with peptide STA02 | x-ray diffraction | A, B | ACE, NI, MG | — |
| 6OVF | Crystal Structure of the Disabled-2 (Dab2) Dab Homology Domain in Complex with Peptide STA03 | x-ray diffraction | A, B | MG, NI | 1 (best 0.65) |
| 6OVF | Crystal structure of the disabled-2 (DAB2) dab homology domain in complex with peptide STA03 | x-ray diffraction | A, B | MG, NI | — |
| P98082 | AlphaFold monomer V2.0 prediction for disabled homolog 2 (P98082) | predicted | A | — | — |
Ligands
Experiment against prediction
- 6O5O chain B against the predicted model P98082: TM-score 1.00, RMSD 0.31 Å
- 6OVF chain B against the predicted model P98082: TM-score 0.99, RMSD 0.44 Å
- 6OVF chain B against the predicted model P98082: TM-score 0.99, RMSD 0.44 Å
- 6O5O chain A against the predicted model P98082: TM-score 0.98, RMSD 0.62 Å
- 6OVF chain A against the predicted model P98082: TM-score 0.98, RMSD 0.66 Å
- 6OVF chain A against the predicted model P98082: TM-score 0.98, RMSD 0.66 Å
- 2LSW chain A against the predicted model P98082: TM-score 0.29, RMSD 3.84 Å
- 2LSW chain A against the predicted model P98082: TM-score 0.29, RMSD 3.84 Å
Elsewhere
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