UniProt P78423
Fractalkine (P78423)
Fractalkine (UniProt P78423): 16 experimental structures on GenesisL1, 2 ligands bound, 16 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- P78423
- Protein
- Fractalkine
- Experimental structures
- 16
- Predicted models
- 0
- Ligands
- 2
- Pockets
- 16 · 4 records with a druggable one
Structures
16 records of P78423 in the MolNFT archive: 16 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1B2T | Solution structure of the CX3C chemokine domain of fractalkine | solution nmr | A | — | — |
| 1B2T | Solution structure of the CX3C chemokine domain of fractalkine | solution nmr | A | — | — |
| 1F2L | Crystal structure of chemokine domain of fractalkine | x-ray diffraction | A, B, C, D | — | — |
| 1F2L | Crystal structure of chemokine domain of fractalkine | x-ray diffraction | A, B, C, D | — | — |
| 4XT1 | Structure of a nanobody-bound viral GPCR bound to human chemokine CX3CL1 | x-ray diffraction | B | — | — |
| 4XT1 | Structure of a nanobody-bound viral GPCR bound to human chemokine CX3CL1 | x-ray diffraction | B | — | — |
| 4XT3 | Structure of a viral GPCR bound to human chemokine CX3CL1 | x-ray diffraction | B | NAG | 3 (best 0.77) |
| 4XT3 | Structure of a viral GPCR bound to human chemokine CX3CL1 | x-ray diffraction | B | — | — |
| 7RKF | Structure of CX3CL1-US28-G11iN18-scFv16 in TL-state | electron microscopy | L | NAG | 3 (best 0.83) |
| 7RKF | Structure of CX3CL1-US28-G11IN18-SCFV16 in tl-state | electron microscopy | L | NAG | — |
| 7RKM | Structure of CX3CL1-US28-gi-SCFV16 in C-state | electron microscopy | L | — | — |
| 7RKN | Structure of CX3CL1-US28-Gi-scFv16 in OC-state | electron microscopy | L | — | 4 (best 0.75) |
| 7RKN | Structure of CX3CL1-US28-gi-SCFV16 in oc-state | electron microscopy | L | — | — |
| 7XBX | Cryo-EM structure of the human chemokine receptor CX3CR1 in complex with CX3CL1 and Gi1 | electron microscopy | R | CLR | 6 (best 0.75) |
| 7XBX | Cryo-EM structure of the human chemokine receptor CX3CR1 in complex with CX3CL1 and GI1 | electron microscopy | R | CLR | — |
| P78423 | AlphaFold monomer V2.0 prediction for fractalkine (P78423) | — | — | — |
Ligands
Experiment against prediction
- 7XBX chain R against the predicted model P49238: TM-score 0.80, RMSD 1.99 Å
- 7XBX chain R against the predicted model P49238: TM-score 0.80, RMSD 1.99 Å
Elsewhere
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