UniProt P70375
Coagulation factor VII (P70375)
Coagulation factor VII (UniProt P70375), EC 3.4.21.21: 6 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound, 3 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P70375
- Protein
- Coagulation factor VII
- EC
- 3.4.21.21
- Experimental structures
- 6
- Predicted models
- 1
- Ligands
- 2
- Pockets
- 3 · 1 record with a druggable one
Structures
7 records of P70375 in the MolNFT archive: 6 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 5KXH | mouse POFUT1 in complex with mouse Factor VII EGF1 and GDP | x-ray diffraction | B | — | — |
| 5KXH | Mouse POFUT1 in complex with mouse factor VII EGF1 and GDP | x-ray diffraction | B | — | — |
| 5KY2 | mouse POFUT1 in complex with O-glucosylated mouse Factor VII EGF1 and GDP | x-ray diffraction | B | BGC | — |
| 5KY2 | Mouse POFUT1 in complex with O-glucosylated mouse factor VII EGF1 and GDP | x-ray diffraction | B | BGC | — |
| 5KY3 | mouse POFUT1 in complex with mouse Factor VII EGF1 mutant (T101A) and GDP-fucose | x-ray diffraction | B | GFB | 3 (best 0.75) |
| 5KY3 | Mouse POFUT1 in complex with mouse factor VII EGF1 mutant (T101A) and GDP-fucose | x-ray diffraction | B | GFB | — |
| P70375 | AlphaFold monomer V2.0 prediction for coagulation factor VII (P70375) | predicted | A | — | — |
Ligands
Experiment against prediction
- 5KY2 chain B against the predicted model P70375: TM-score 0.91, RMSD 1.02 Å
- 5KY2 chain B against the predicted model P70375: TM-score 0.91, RMSD 1.02 Å
- 5KY3 chain B against the predicted model P70375: TM-score 0.91, RMSD 0.65 Å
- 5KY3 chain B against the predicted model P70375: TM-score 0.91, RMSD 0.65 Å
- 5KXH chain B against the predicted model P70375: TM-score 0.89, RMSD 1.40 Å
- 5KXH chain B against the predicted model P70375: TM-score 0.89, RMSD 1.40 Å
Elsewhere
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