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UniProt P70303

CTP synthase 2 (P70303)

CTP synthase 2 (UniProt P70303): 3 experimental structures and 1 predicted model on GenesisL1, 3 ligands bound, 3 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.

UniProt
P70303
Protein
CTP synthase 2
Experimental structures
3
Predicted models
1
Ligands
3
Pockets
3 · 1 record with a druggable one

Structures

4 records of P70303 in the MolNFT archive: 3 experimental, 1 predicted.

EntryTitleMethodChainsLigandsPockets
7MIUMouse CTPS2 bound to inhibitor R80electron microscopyD, C, H, GZG4, MG, UTP—
7MIVMouse CTPS2-I250T bound to inhibitor R80electron microscopyD, C, H, GMG, UTP, ZG4—
7MIVMouse CTPS2-I250T bound to inhibitor R80electron microscopyD, C, H, GMG, UTP, ZG4—
P70303AlphaFold monomer V2.0 prediction for CTP synthase 2 (P70303)predictedA—3 (best 0.69)

Ligands

  • MG · Magnesium ion · in 3 records
  • UTP · Uridine 5'-triphosphate · in 3 records
  • ZG4 · N-(1-{2-[(cyclopropanesulfonyl)amino]-1,3-thiazol-4-yl}cyclopropyl)-5-(6-ethoxypyrazin-2-yl)pyridine-2-carboxamide · in 3 records

Experiment against prediction

Elsewhere

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