UniProt P69834
2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase, chloroplastic (P69834)
2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase, chloroplastic (UniProt P69834), EC 2.7.7.60: 24 experimental structures and 1 predicted model on GenesisL1, 5 ligands bound, 2 pockets. Binding sites, druggability and…
- UniProt
- P69834
- Protein
- 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase, chloroplastic
- EC
- 2.7.7.60
- Experimental structures
- 24
- Predicted models
- 1
- Ligands
- 5
- Pockets
- 2 · 1 record with a druggable one
Structures
25 records of P69834 in the MolNFT archive: 24 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2YC3 | Inhibitors of the herbicidal target IspD | x-ray diffraction | A | — | — |
| 2YC3 | Inhibitors of the herbicidal target ispd | x-ray diffraction | A | — | — |
| 2YC5 | Inhibitors of the herbicidal target IspD | x-ray diffraction | A | — | — |
| 2YC5 | Inhibitors of the herbicidal target ispd | x-ray diffraction | A | — | — |
| 2YCM | Inhibitors of herbicidal target IspD | x-ray diffraction | A | — | — |
| 2YCM | Inhibitors of herbicidal target ispd | x-ray diffraction | A | — | — |
| 4NAI | Arabidopsis thaliana IspD apo | x-ray diffraction | A | — | — |
| 4NAI | Arabidopsis thaliana ispd apo | x-ray diffraction | A | — | — |
| 4NAK | Arabidopsis thaliana IspD in complex with pentabromo-pseudilin | x-ray diffraction | A | — | — |
| 4NAK | Arabidopsis thaliana ispd in complex with pentabromo-pseudilin | x-ray diffraction | A | — | — |
| 4NAL | Arabidopsis thaliana IspD in complex with tribromodichloro-pseudilin | x-ray diffraction | A | — | — |
| 4NAL | Arabidopsis thaliana ispd in complex with tribromodichloro-pseudilin | x-ray diffraction | A | — | — |
| 4NAN | Arabidopsis thaliana IspD in complex with tetrabromo-pseudilin | x-ray diffraction | A | — | — |
| 4NAN | Arabidopsis thaliana ispd in complex with tetrabromo-pseudilin | x-ray diffraction | A | — | — |
| 5MRM | Arabidopsis thaliana IspD in complex with Isoxazole (4) | x-ray diffraction | A | Q9T, K, CD | — |
| 5MRM | Arabidopsis thaliana ispd in complex with isoxazole (4) | x-ray diffraction | A | Q9T, K, CD | — |
| 5MRN | Arabidopsis thaliana IspD Glu258Ala Mutant | x-ray diffraction | A | K, CD | — |
| 5MRN | Arabidopsis thaliana ispd GLU258ALA mutant | x-ray diffraction | A | K, CD | — |
| 5MRO | Arabidopsis thaliana IspD Glu258Ala mutant in complex with Azolopyrimidine (1) | x-ray diffraction | A | Q9P, K, CD | — |
| 5MRO | Arabidopsis thaliana ispd GLU258ALA mutant in complex with azolopyrimidine (1) | x-ray diffraction | A | Q9P, K, CD | — |
| 5MRP | Arabidopsis thaliana IspD Glu258Ala mutant in complex with Azolopyrimidine (2) | x-ray diffraction | A | 6BC, K, CD | 2 (best 0.75) |
| 5MRP | Arabidopsis thaliana ispd GLU258ALA mutant in complex with azolopyrimidine (2) | x-ray diffraction | A | 6BC, K, CD | — |
| 5MRQ | Arabidopsis thaliana IspD Asp262Ala Mutant | x-ray diffraction | A | CD | — |
| 5MRQ | Arabidopsis thaliana ispd ASP262ALA mutant | x-ray diffraction | A | CD | — |
| P69834 | AlphaFold monomer V2.0 prediction for 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase… | predicted | A | — | — |
Ligands
Experiment against prediction
- 4NAI chain A against the predicted model P69834: TM-score 0.98, RMSD 0.90 Å
- 4NAI chain A against the predicted model P69834: TM-score 0.98, RMSD 0.90 Å
- 5MRN chain A against the predicted model P69834: TM-score 0.97, RMSD 1.01 Å
- 5MRN chain A against the predicted model P69834: TM-score 0.97, RMSD 1.01 Å
- 5MRQ chain A against the predicted model P69834: TM-score 0.97, RMSD 1.02 Å
- 5MRQ chain A against the predicted model P69834: TM-score 0.97, RMSD 1.02 Å
- 5MRP chain A against the predicted model P69834: TM-score 0.96, RMSD 1.26 Å
- 5MRP chain A against the predicted model P69834: TM-score 0.96, RMSD 1.26 Å
- 2YCM chain A against the predicted model P69834: TM-score 0.96, RMSD 1.33 Å
- 2YCM chain A against the predicted model P69834: TM-score 0.96, RMSD 1.33 Å
Elsewhere
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